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Indian J Urol. 2009 Jul;25(3):398-400. doi: 10.4103/0970-1591.56180.

Bleomycin induced urethral stricture in Hodgkin's disease.

Indian journal of urology : IJU : journal of the Urological Society of India

Ritesh Tapkire, N Kathiresan, B Satheesan

Affiliations

  1. Department of Surgical Oncology, Cancer Institute (W.I.A.), Adyar, Chennai, India.

PMID: 19881140 PMCID: PMC2779969 DOI: 10.4103/0970-1591.56180

Abstract

Bleomycin is a glycoprotein that is extensively used in combination with other anti-cancer agents because of its relative lack of hematological and gastrointestinal toxicity. However, pulmonary toxicity is common with bleomycin and limits its therapeutic utility. Urethral stricture as a result of bleomycin toxicity has not been reported in literature. In this case report, a young male patient who developed urethral stricture after bleomycin-based chemotherapy is described and the possible effects of bleomycin on the urethra are discussed.

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