Display options
Share it on

Evid Based Complement Alternat Med. 2011;2011:639260. doi: 10.1093/ecam/nep170. Epub 2011 Mar 10.

Reporting experiments in homeopathic basic research-description of the checklist development.

Evidence-based complementary and alternative medicine : eCAM

B Stock-Schröer, H Albrecht, L Betti, G Dobos, C Endler, K Linde, R Lüdtke, F Musial, R van Wijk, C Witt, S Baumgartner

Affiliations

  1. Karl and Veronica Carstens-Foundation, D-Essen, Germany.

PMID: 19884113 PMCID: PMC3136753 DOI: 10.1093/ecam/nep170

Abstract

The objective of this study was to develop a criteria catalogue serving as a guideline for authors to improve quality of reporting experiments in basic research in homeopathy. A Delphi Process was initiated including three rounds of adjusting and phrasing plus two consensus conferences. European researchers who published experimental work within the last 5 years were involved. A checklist for authors provide a catalogue with 23 criteria. The "Introduction" should focus on underlying hypotheses, the homeopathic principle investigated and state if experiments are exploratory or confirmatory. "Materials and methods" should comprise information on object of investigation, experimental setup, parameters, intervention and statistical methods. A more detailed description on the homeopathic substances, for example, manufacture, dilution method, starting point of dilution is required. A further result of the Delphi process is to raise scientists' awareness of reporting blinding, allocation, replication, quality control and system performance controls. The part "Results" should provide the exact number of treated units per setting which were included in each analysis and state missing samples and drop outs. Results presented in tables and figures are as important as appropriate measures of effect size, uncertainty and probability. "Discussion" in a report should depict more than a general interpretation of results in the context of current evidence but also limitations and an appraisal of aptitude for the chosen experimental model. Authors of homeopathic basic research publications are encouraged to apply our checklist when preparing their manuscripts. Feedback is encouraged on applicability, strength and limitations of the list to enable future revisions.

References

  1. Control Clin Trials. 1995 Feb;16(1):62-73 - PubMed
  2. JAMA. 1999 Sep 15;282(11):1054-60 - PubMed
  3. J Clin Epidemiol. 2009 Jun;62(6):597-608.e4 - PubMed
  4. Complement Ther Med. 2007 Jun;15(2):128-38 - PubMed
  5. JAMA. 1996 Aug 28;276(8):637-9 - PubMed
  6. Complement Ther Med. 2001 Dec;9(4):246-9 - PubMed
  7. PLoS Med. 2008 Jan 22;5(1):e20 - PubMed
  8. Contemp Clin Trials. 2008 Sep;29(5):727-31 - PubMed
  9. Nat Biotechnol. 2008 Aug;26(8):889-96 - PubMed
  10. Hum Exp Toxicol. 1994 Jul;13(7):481-92 - PubMed
  11. Evid Based Complement Alternat Med. 2011;2011:383245 - PubMed
  12. JAMA. 2003 Aug 27;290(8):1062-70 - PubMed
  13. Am J Orthod Dentofacial Orthop. 2005 Dec;128(6):681-5; discussion 686 - PubMed
  14. Forsch Komplementarmed. 1998 Feb;5(1):27-32 - PubMed
  15. Control Clin Trials. 1996 Feb;17(1):1-12 - PubMed
  16. Explore (NY). 2005 Jan;1(1):40-5 - PubMed
  17. BMJ. 2009 Jan 19;338:a3152 - PubMed
  18. J Altern Complement Med. 2003 Feb;9(1):113-32 - PubMed
  19. Radiology. 2003 Jan;226(1):24-8 - PubMed
  20. Lancet. 1999 Nov 27;354(9193):1896-900 - PubMed
  21. J Altern Complement Med. 2007 Jan-Feb;13(1):19-23 - PubMed
  22. Evid Based Complement Alternat Med. 2009 Dec;6(4):441-8 - PubMed
  23. Ann Intern Med. 2006 Mar 7;144(5):364-7 - PubMed
  24. Ann Intern Med. 2007 Oct 16;147(8):W163-94 - PubMed
  25. J Am Podiatr Med Assoc. 2001 Sep;91(8):437-42 - PubMed
  26. Complement Ther Med. 2008 Aug;16(4):183-91 - PubMed
  27. Maturitas. 2009 May 20;63(1):4-6 - PubMed
  28. Homeopathy. 2007 Oct;96(4):247-51 - PubMed
  29. J Clin Epidemiol. 2009 Oct;62(10):1006-12 - PubMed
  30. PLoS One. 2008 Feb 13;3(2):e1577 - PubMed
  31. BMJ. 2008 Nov 11;337:a2390 - PubMed
  32. J Altern Complement Med. 2007 Nov;13(9):939-43 - PubMed

Publication Types