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Strauss BS, Stetson CA. STUDIES ON THE EFFECT OF CERTAIN MACROMOLECULAR SUBSTANCES ON THE RESPIRATORY ACTIVITY OF THE LEUCOCYTES OF PERIPHERAL BLOOD. J Exp Med. 1960;112(4):653-69doi: 10.1084/jem.112.4.653.
Strauss, B. S., & Stetson, C. A. (1960). STUDIES ON THE EFFECT OF CERTAIN MACROMOLECULAR SUBSTANCES ON THE RESPIRATORY ACTIVITY OF THE LEUCOCYTES OF PERIPHERAL BLOOD. The Journal of experimental medicine, 112(4), 653-69. https://doi.org/10.1084/jem.112.4.653
Strauss, B S, and Stetson, C A. "STUDIES ON THE EFFECT OF CERTAIN MACROMOLECULAR SUBSTANCES ON THE RESPIRATORY ACTIVITY OF THE LEUCOCYTES OF PERIPHERAL BLOOD." The Journal of experimental medicine vol. 112,4 (1960): 653-69. doi: https://doi.org/10.1084/jem.112.4.653
Strauss BS, Stetson CA. STUDIES ON THE EFFECT OF CERTAIN MACROMOLECULAR SUBSTANCES ON THE RESPIRATORY ACTIVITY OF THE LEUCOCYTES OF PERIPHERAL BLOOD. J Exp Med. 1960 Sep 30;112(4):653-69. doi: 10.1084/jem.112.4.653. PMID: 19867179; PMCID: PMC2137241.
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J Exp Med. 1960 Sep 30;112(4):653-69. doi: 10.1084/jem.112.4.653.

STUDIES ON THE EFFECT OF CERTAIN MACROMOLECULAR SUBSTANCES ON THE RESPIRATORY ACTIVITY OF THE LEUCOCYTES OF PERIPHERAL BLOOD.

The Journal of experimental medicine

B S Strauss, C A Stetson

Affiliations

  1. Department of Pathology, New York University School of Medicine, New York.

PMID: 19867179 PMCID: PMC2137241 DOI: 10.1084/jem.112.4.653

Abstract

The oxygen, uptake of lightly heparinized human blood was found to increase markedly upon the addition of bacterial endotoxins, soluble antigen-antibody complexes, or polystyrene latex particles. The effect apparently reflects a transitory stimulation of respiratory activity of the blood leucocytes. The effect did not occur in the presence of anticoagulant amounts of citrate or ethylenediaminetetraacetate, was inhibited by iodoacetate and fluoride ions, and may be related to the energy-yielding processes involved in histamine release or phagocytosis.

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