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J Exp Med. 1911 Sep 01;14(3):217-34. doi: 10.1084/jem.14.3.217.

STUDIES WITH THE ELECTROCARDIOGRAPH ON THE ACTION OF THE VAGUS NERVE ON THE HUMAN HEART : I. THE EFFECT OF MECHANICAL STIMULATION OF THE VAGUS NERVE.

The Journal of experimental medicine

G C Robinson, G Draper

Affiliations

  1. Hospital of the Rockefeller Institute for Medical Research, New York.

PMID: 19867466 PMCID: PMC2124771 DOI: 10.1084/jem.14.3.217

Abstract

In hearts showing auricular fibrillation mechanical stimulation of the right vagus nerve causes, as a rule, marked slowing or stoppage of ventricular rhythm, without producing any appreciable effect in the electrocardiographic record of the auricular fibrillation. The ventricular pauses are apparently due to the blocking of stimuli from the auricles. The force of ventricular systole is distinctly weakened for several beats after vagus stimulation, and ectopic ventricular systoles have been seen in several instances, apparently the result of the vagus action. There may, in some cases, be lowered excitability of the ventricles, while no constant change is seen in the size of the electrical complexes representing ventricular systole.

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