J Exp Med. 1919 May 01;29(5):445-9. doi: 10.1084/jem.29.5.445.
The Journal of experimental medicine
H Haessler, M G Stebbins
PMID: 19868329 PMCID: PMC2126335 DOI: 10.1084/jem.29.5.445
1. Within certain limits the clotting time of blood, of blood plasma, and of solutions of fibrin to which bile salts have been added, is proportional to the quantity of bile present. 2. The bile interferes with the conversion of fibrinogen into fibrin and not with the formation of thrombin.