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J Exp Med. 1933 Aug 31;58(3):277-87. doi: 10.1084/jem.58.3.277.

VARYING HEMOLYTIC AND CONSTANT COMBINING CAPACITY OF STREPTOLYSINS; INFLUENCE ON TESTING FOR ANTISTREPTOLYSINS.

The Journal of experimental medicine

B E Hodge, H F Swift

Affiliations

  1. Hospital of The Rockefeller Institute for Medical Research.

PMID: 19870195 PMCID: PMC2132299 DOI: 10.1084/jem.58.3.277

Abstract

Certain properties of streptolysin in respect of hemolytic power and capacity for combining with antistreptolysins have been determined. The hemolytic strength may vary markedly, while under suitable conditions the combining power is constant. This stability of combining capacity makes it possible to prepare a large amount of streptolysin, standardize it against sera of known antistreptolysin strength, and use it as a reagent over a considerable period for testing the antistreptolysin content of unknown sera. A modified technique for making these tests is described.

References

  1. J Exp Med. 1926 Jul 31;44(2):241-60 - PubMed
  2. J Exp Med. 1932 Jan 31;55(2):267-80 - PubMed

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