Display options
Share it on

Int J Cell Biol. 2009;2009:906507. doi: 10.1155/2009/906507. Epub 2009 Mar 29.

Cellular therapy for repair of cardiac damage after acute myocardial infarction.

International journal of cell biology

Matthew M Cook, Katarina Kollar, Gary P Brooke, Kerry Atkinson

Affiliations

  1. Adult Stem Cell Laboratory, Mater Medical Research Institute, South Brisbane, QLD 4101, Australia.

PMID: 20130765 PMCID: PMC2809316 DOI: 10.1155/2009/906507

Abstract

Cardiovascular diseases, particularly acute myocardial infarction, are the leading causes of death worldwide. Important advances have been made in the secondary treatment for cardiovascular diseases such as heart transplantation and medical and surgical therapies. Although these therapies alleviate symptoms, and may even improve survival, none can reverse the disease process and directly repair the lasting damage. Thus, the cure of cardiovascular diseases remains a major unmet medical need. Recently, cellular therapy has been proposed as a candidate treatment for this. Many stem and progenitor cell populations have each been suggested as a potential basis for such therapy. This review assesses some of the more notable exogenous adult cell candidates and provides insights into the mechanisms by which they may mediate improvement in cardiac function following acute myocardial infarction. Research into the cellular therapy field is of great importance for the further planning of clinical trials for cardiac cellular myoplasty.

References

  1. Circulation. 2003 Feb 25;107(7):1024-32 - PubMed
  2. J Cell Physiol. 2000 Jul;184(1):58-69 - PubMed
  3. Exp Hematol. 2006 Aug;34(8):996-1009 - PubMed
  4. Transplantation. 1968 Mar;6(2):230-47 - PubMed
  5. Blood. 1992 Oct 1;80(7):1693-701 - PubMed
  6. Antioxid Redox Signal. 2006 Nov-Dec;8(11-12):1907-39 - PubMed
  7. Cancer Cell. 2005 Sep;8(3):211-26 - PubMed
  8. J Surg Res. 2000 Apr;89(2):189-95 - PubMed
  9. Circulation. 2002 Jan 1;105(1):93-8 - PubMed
  10. Catheter Cardiovasc Interv. 2005 Jul;65(3):321-9 - PubMed
  11. Cytotherapy. 2003;5(6):485-9 - PubMed
  12. Injury. 2006 Apr;37 Suppl 1:S5-12 - PubMed
  13. Nature. 2001 Apr 5;410(6829):701-5 - PubMed
  14. Science. 1997 Feb 14;275(5302):964-7 - PubMed
  15. Cytotherapy. 2005;7(5):393-5 - PubMed
  16. J Cell Physiol. 1999 Oct;181(1):67-73 - PubMed
  17. Blood. 2001 Oct 15;98(8):2396-402 - PubMed
  18. Blood. 2005 Sep 1;106(5):1525-31 - PubMed
  19. Nature. 2004 Apr 8;428(6983):668-73 - PubMed
  20. Stem Cells Dev. 2008 Dec;17(6):1095-107 - PubMed
  21. Nature. 2002 Jul 4;418(6893):41-9 - PubMed
  22. Science. 1997 Apr 4;276(5309):71-4 - PubMed
  23. J Immunol. 2007 Jun 1;178(11):7405-11 - PubMed
  24. Circ Res. 2003 Nov 28;93(11):1023-5 - PubMed
  25. Circ Res. 2004 Sep 3;95(5):449-58 - PubMed
  26. J Cell Physiol. 2006 Jul;208(1):64-76 - PubMed
  27. Ann N Y Acad Sci. 2007 Jun;1106:64-75 - PubMed
  28. Recent Prog Horm Res. 2004;59:51-71 - PubMed
  29. Free Radic Biol Med. 2001 Oct 1;31(7):902-10 - PubMed
  30. Cell. 2005 Jul 1;121(7):1109-21 - PubMed
  31. Nat Med. 2003 Jun;9(6):702-12 - PubMed
  32. Blood. 2005 Oct 1;106(7):2347-55 - PubMed
  33. Exp Hematol. 2000 Aug;28(8):875-84 - PubMed
  34. Transplantation. 2004 Jul 15;78(1):83-8 - PubMed
  35. Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):1142-7 - PubMed
  36. Blood. 2008 Nov 1;112(9):3543-53 - PubMed
  37. Blood. 2006 Jul 15;108(2):737-44 - PubMed
  38. Am J Physiol Heart Circ Physiol. 2006 Aug;291(2):H886-93 - PubMed
  39. Nat Med. 2004 May;10(5):494-501 - PubMed
  40. Yan Ke Xue Bao. 2005 Sep;21(3):158-62, 178 - PubMed
  41. Circulation. 2005 Jan 18;111(2):150-6 - PubMed
  42. Blood. 2004 Nov 1;104(9):2752-60 - PubMed
  43. Nat Med. 2001 Apr;7(4):430-6 - PubMed
  44. Blood. 2006 Dec 1;108(12):3662-7 - PubMed
  45. Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6246-51 - PubMed
  46. Science. 1996 Jul 12;273(5272):242-5 - PubMed
  47. Ciba Found Symp. 1988;136:42-60 - PubMed
  48. J Exp Med. 1998 Aug 3;188(3):465-74 - PubMed
  49. Blood. 2007 Jun 15;109(12):5276-85 - PubMed
  50. Lancet. 2004 May 1;363(9419):1439-41 - PubMed
  51. Circulation. 2003 Jan 28;107(3):461-8 - PubMed
  52. Arch Intern Med. 2007 May 28;167(10):989-97 - PubMed
  53. Cell Tissue Kinet. 1987 May;20(3):263-72 - PubMed
  54. Transplantation. 2003 Oct 27;76(8):1208-13 - PubMed
  55. Cardiovasc Res. 2002 Jan;53(1):31-47 - PubMed
  56. Blood. 2007 Apr 15;109(8):3147-51 - PubMed
  57. Nat Immunol. 2006 Nov;7(11):1225-33 - PubMed
  58. Blood. 2000 May 15;95(10):3106-12 - PubMed
  59. Lancet. 2008 May 10;371(9624):1579-86 - PubMed
  60. Circulation. 2007 Sep 4;116(10):1176-84 - PubMed
  61. J Cell Physiol. 2002 Jan;190(1):54-62 - PubMed
  62. Stem Cells. 2005 Jun-Jul;23(6):791-804 - PubMed
  63. Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1283-8 - PubMed
  64. Eur Heart J. 2006 Sep;27(18):2247-55 - PubMed
  65. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3422-7 - PubMed
  66. Am J Pathol. 1993 Sep;143(3):678-84 - PubMed
  67. Transfus Med Hemother. 2008;35(4):279-285 - PubMed
  68. Circ Res. 2004 Feb 6;94(2):230-8 - PubMed
  69. Cytotherapy. 2006;8(4):315-7 - PubMed
  70. Cell Stem Cell. 2008 Sep 11;3(3):301-13 - PubMed
  71. Circulation. 2005 Mar 8;111(9):1175-83 - PubMed
  72. Nature. 1977 Oct 27;269(5631):804-6 - PubMed
  73. Blood. 2004 Mar 1;103(5):1662-8 - PubMed
  74. Circ Res. 2005 Sep 30;97(7):663-73 - PubMed
  75. Science. 1999 Apr 2;284(5411):143-7 - PubMed
  76. Br J Haematol. 2009 Feb;144(4):571-9 - PubMed
  77. Exp Hematol. 2002 Feb;30(2):176-85 - PubMed
  78. Semin Cell Dev Biol. 2007 Dec;18(6):846-58 - PubMed
  79. Stem Cells Dev. 2004 Aug;13(4):344-9 - PubMed
  80. Placenta. 2007 Nov-Dec;28(11-12):1174-81 - PubMed
  81. Cancer Treat Rev. 2003 Aug;29(4):283-90 - PubMed
  82. Transplantation. 2006 May 27;81(10):1390-7 - PubMed
  83. Blood. 2006 Mar 1;107(5):1878-87 - PubMed
  84. Blood. 2004 Mar 1;103(5):1669-75 - PubMed
  85. Blood. 2007 Mar 1;109(5):1801-9 - PubMed
  86. Cardiovasc Res. 2005 Jan 1;65(1):52-63 - PubMed
  87. Regen Med. 2007 Jan;2(1):63-8 - PubMed
  88. Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11474-9 - PubMed
  89. Exp Neurol. 2002 Mar;174(1):11-20 - PubMed
  90. Annu Rev Med. 2003;54:491-512 - PubMed
  91. Circulation. 2001 Feb 6;103(5):634-7 - PubMed
  92. Arthritis Rheum. 2003 Dec;48(12):3464-74 - PubMed
  93. Cell Stem Cell. 2008 Apr 10;2(4):313-9 - PubMed
  94. Arterioscler Thromb Vasc Biol. 2008 Feb;28(2):208-16 - PubMed
  95. Blood. 2006 Oct 1;108(7):2438-45 - PubMed
  96. Stem Cell Res. 2007 Nov;1(2):129-37 - PubMed
  97. Arterioscler Thromb Vasc Biol. 2006 Feb;26(2):257-66 - PubMed
  98. Stem Cells. 2008 Sep;26(9):2287-99 - PubMed
  99. Circ Res. 1998 Sep 7;83(5):516-22 - PubMed
  100. Proc Natl Acad Sci U S A. 2007 Nov 6;104(45):17783-8 - PubMed
  101. Exp Hematol. 2002 Aug;30(8):870-8 - PubMed
  102. Arterioscler Thromb Vasc Biol. 2004 Feb;24(2):288-93 - PubMed
  103. Nature. 2003 Oct 30;425(6961):968-73 - PubMed
  104. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8932-7 - PubMed
  105. Circ Res. 2000 Sep 1;87(5):378-84 - PubMed
  106. Stem Cells Dev. 2008 Oct;17(5):929-40 - PubMed
  107. Am J Pathol. 2006 Feb;168(2):529-41 - PubMed
  108. Circulation. 2004 Mar 30;109(12):1543-9 - PubMed
  109. Annu Rev Pathol. 2007;2:307-39 - PubMed
  110. Arch Med Res. 2003 Nov-Dec;34(6):461-75 - PubMed
  111. Br J Haematol. 2007 Sep;138(6):792-801 - PubMed
  112. Transplantation. 2005 Jun 15;79(11):1607-14 - PubMed
  113. Intern Med J. 2005 Jun;35(6):348-56 - PubMed
  114. Curr Opin Hematol. 2003 May;10(3):214-9 - PubMed
  115. Cell. 2003 Sep 19;114(6):763-76 - PubMed
  116. FEBS Lett. 2007 Aug 21;581(21):3961-6 - PubMed
  117. Blood. 2005 Mar 1;105(5):2214-9 - PubMed
  118. J Mol Cell Cardiol. 2003 Sep;35(9):1113-9 - PubMed
  119. Circulation. 2005 Sep 13;112(11):1618-27 - PubMed
  120. Am J Respir Cell Mol Biol. 1999 Feb;20(2):237-47 - PubMed
  121. Stem Cells Dev. 2004 Dec;13(6):665-76 - PubMed
  122. Nature. 2004 Apr 8;428(6983):664-8 - PubMed

Publication Types