Display options
Share it on

Indian J Occup Environ Med. 2009 Apr;13(1):3-10. doi: 10.4103/0019-5278.50716.

The exposure to and health effects of antimony.

Indian journal of occupational and environmental medicine

Ross G Cooper, Adrian P Harrison

Affiliations

  1. Division of Physiology, Birmingham City University, 704 Baker Building, Franchise Street, Perry Barr, Birmingham B42 2SU, UK.

PMID: 20165605 PMCID: PMC2822166 DOI: 10.4103/0019-5278.50716

Abstract

CONTEXT: This minireview describes the health effects of antimony exposure in the workplace and the environment.

AIM: To collate information on the consequences of occupational and environmental exposure to antimony on physiological function and well-being.

METHODS: The criteria used in the current minireview for selecting articles were adopted from proposed criteria in The International Classification of Functioning, Disability and Health. Articles were classified from an acute and chronic exposure and toxicity thrust.

RESULTS: The proportion of utilised and non-utilised articles was tabulated. Antimony toxicity is dependent on the exposure dose, duration, route (breathing, eating, drinking, or skin contact), other chemical exposures, age, sex, nutritional status, family traits, life style, and state of health. Chronic exposure to antimony in the air at levels of 9 mg/m(3) may exacerbate irritation of the eyes, skin, and lungs. Long-term inhalation of antimony can potentiate pneumoconiosis, altered electrocardiograms, stomach pain, diarrhea, vomiting, and stomach ulcers, results which were confirmed in laboratory animals. Although there were investigations of the effect of antimony in sudden infant death syndrome, current findings suggest no link. Antimony trioxide exposure is predominant in smelters. Mining and exposure via glass working, soldering, and brazing are also important.

CONCLUSION: Antimony has some useful but undoubtedly harmful effects on health and well-being and measures need to be taken to prevent hazardous exposure of the like. Its biological monitoring in the workplace is essential.

Keywords: Antimony; environment; exposure; health; occupation

References

  1. Gig Tr Prof Zabol. 1992;(5):13-5 - PubMed
  2. J Occup Environ Med. 2004 Sep;46(9):931-6 - PubMed
  3. Toxicol Lett. 2006 Jan 5;160(2):158-70 - PubMed
  4. Chem Biol Interact. 1997 Nov 28;107(3):131-44 - PubMed
  5. Water Res. 2008 Feb;42(3):551-6 - PubMed
  6. Environ Health Perspect. 2005 Feb;113(2):164-9 - PubMed
  7. Mutat Res. 1996 Oct;366(1):1-8 - PubMed
  8. Arch Environ Health. 2004 May;59(5):245-9 - PubMed
  9. Cancer Causes Control. 1997 May;8(3):371-85 - PubMed
  10. Environ Health Perspect. 1998 Jan;106(1):33-9 - PubMed
  11. Arch Dis Child. 1997 May;76(5):432-6 - PubMed
  12. Environ Pollut. 2003;124(1):93-100 - PubMed
  13. Br J Ind Med. 1991 Feb;48(2):93-7 - PubMed
  14. J Environ Monit. 2004 Dec;6(12):985-91 - PubMed
  15. Sci Total Environ. 1988 Nov 1;77(1):1-13 - PubMed
  16. Zentralbl Hyg Umweltmed. 1998 Feb;201(1):103-20 - PubMed
  17. Hum Exp Toxicol. 1999 Oct;18(10):607-13 - PubMed
  18. Environ Health Perspect. 2004 Jun;112(8):809-11 - PubMed
  19. Med Tr Prom Ekol. 1996;(4):12-5 - PubMed
  20. Hum Exp Toxicol. 1998 Mar;17(3):138-9 - PubMed
  21. FEMS Microbiol Lett. 1998 Jan 15;158(2):261-5 - PubMed
  22. Adverse Drug React Acute Poisoning Rev. 1987 Summer;6(2):67-90 - PubMed
  23. Int Arch Occup Environ Health. 1998 May;71(3):221-4 - PubMed
  24. Mutat Res. 1998 Feb 13;412(3):213-8 - PubMed
  25. J Am Coll Cardiol. 1999 May;33(6):1578-83 - PubMed
  26. J Environ Monit. 2002 Dec;4(6):1034-9 - PubMed
  27. Hum Exp Toxicol. 1998 Mar;17(3):140-3 - PubMed
  28. Vesalius. 2003 Jun;9(1):13-9 - PubMed
  29. Scand J Work Environ Health. 1993;19 Suppl 1:95-100 - PubMed
  30. Food Addit Contam. 2007 Aug;24(8):860-8 - PubMed
  31. Mutat Res. 2003 Dec 10;533(1-2):135-52 - PubMed
  32. Am J Ind Med. 1995 May;27(5):759-70 - PubMed
  33. Scand J Work Environ Health. 1982 Sep;8(3):201-8 - PubMed
  34. Environ Sci Technol. 2008 Apr 15;42(8):2937-42 - PubMed
  35. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2008 Jul;25(7):831-40 - PubMed
  36. Clin Chem. 1987 Nov;33(11):2081-2 - PubMed
  37. Int Arch Occup Environ Health. 1983;51(3):199-207 - PubMed
  38. Am J Ind Med. 2003 Oct;44(4):405-12 - PubMed
  39. Occup Med (Lond). 2007 Jun;57(4):238-45 - PubMed
  40. Sci Total Environ. 2008 Aug 1;400(1-3):270-82 - PubMed
  41. Environ Geochem Health. 2007 Jun;29(3):209-19 - PubMed
  42. J Trace Elem Med Biol. 2002;16(1):33-9 - PubMed
  43. Rapid Commun Mass Spectrom. 2005;19(21):3131-8 - PubMed
  44. Food Addit Contam. 1999 Sep;16(9):391-403 - PubMed
  45. Am J Ind Med. 1998 Jul;34(1):65-72 - PubMed
  46. J Occup Med. 1993 Apr;35(4):392-5 - PubMed
  47. J Environ Monit. 2005 Dec;7(12):1245-50 - PubMed
  48. Toxicology. 1998 Aug 21;129(2-3):113-23 - PubMed
  49. Med Pr. 2002;53(6):473-80 - PubMed
  50. Hum Exp Toxicol. 1998 Apr;17(4):231-8 - PubMed
  51. Midwifery Today Int Midwife. 2002 Spring;(61):21-2 - PubMed
  52. Scand J Work Environ Health. 1993;19 Suppl 1:101-3 - PubMed
  53. Vet Hum Toxicol. 2004 Dec;46(6):331-3 - PubMed
  54. Environ Mol Mutagen. 2002;40(3):184-9 - PubMed

Publication Types