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Choi EY, Cho YO. Effect of vitamin B(6) deficiency on antioxidative status in rats with exercise-induced oxidative stress. Nutr Res Pract. 2009;3(3):208-11doi: 10.4162/nrp.2009.3.3.208.
Choi, E. Y., & Cho, Y. O. (2009). Effect of vitamin B(6) deficiency on antioxidative status in rats with exercise-induced oxidative stress. Nutrition research and practice, 3(3), 208-11. https://doi.org/10.4162/nrp.2009.3.3.208
Choi, Eun-Young, and Cho, Youn-Ok. "Effect of vitamin B(6) deficiency on antioxidative status in rats with exercise-induced oxidative stress." Nutrition research and practice vol. 3,3 (2009): 208-11. doi: https://doi.org/10.4162/nrp.2009.3.3.208
Choi EY, Cho YO. Effect of vitamin B(6) deficiency on antioxidative status in rats with exercise-induced oxidative stress. Nutr Res Pract. 2009;3(3):208-11. doi: 10.4162/nrp.2009.3.3.208. Epub 2009 Sep 30. PMID: 20090886; PMCID: PMC2808720.
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Nutr Res Pract. 2009;3(3):208-11. doi: 10.4162/nrp.2009.3.3.208. Epub 2009 Sep 30.

Effect of vitamin B(6) deficiency on antioxidative status in rats with exercise-induced oxidative stress.

Nutrition research and practice

Eun-Young Choi, Youn-Ok Cho

Affiliations

  1. Department of Food and Nutrition, Duksung Women's University, 419 Ssangmun-dong, Dobong-gu, Seoul 132-714, Korea.

PMID: 20090886 PMCID: PMC2808720 DOI: 10.4162/nrp.2009.3.3.208

Abstract

This study investigated the effect of vitamin B(6) deficiency on antioxidant enzyme activities and lipid profile in rats with exercise-induced oxidative stress. Forty eight rats were fed either a vitamin B(6) deficient diet (B6-) or a control diet (control) for 4 weeks and then subdivided into 3 groups: pre-exercise (PreE); post-exercise (PostE); recess after exercise (recessE). Compared to those of control group, plasma catalase and hepatic cytosol superoxide dismutase (SOD, EC 1.15.1.1) activities of B6- group were lower regardless of exercise. The ratio of reduced glutathione/oxidized glutathione (GSH/GSSG) of B6- group was lower in PreE and there was no difference between PostE and recessE. The level of malondialdehyde (MDA) of B6- was significantly higher in PreE and PostE. High-density lipoprotein-cholesterol (HDL-C) level of B6- group was lower regardless of exercise. Atherosclerotic index of B6- group was higher in PreE and there was no difference between PostE and recessE. It is suggested that a reduction in antioxidative status caused by vitamin B(6) deficiency may be aggravated under exercise-induced oxidative stress.

Keywords: Vitamin B6 deficiency; antioxidative enzymes; exercise; oxidative stress

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