Display options
Cite
Fulda S, Gorman AM, Hori O, et al. Cellular stress responses: cell survival and cell death. Int J Cell Biol. 2010;2010:214074doi: 10.1155/2010/214074.
Fulda, S., Gorman, A. M., Hori, O., & Samali, A. (2010). Cellular stress responses: cell survival and cell death. International journal of cell biology, 2010214074. https://doi.org/10.1155/2010/214074
Fulda, Simone, et al. "Cellular stress responses: cell survival and cell death." International journal of cell biology vol. 2010 (2010): 214074. doi: https://doi.org/10.1155/2010/214074
Fulda S, Gorman AM, Hori O, Samali A. Cellular stress responses: cell survival and cell death. Int J Cell Biol. 2010;2010:214074. doi: 10.1155/2010/214074. Epub 2010 Feb 21. PMID: 20182529; PMCID: PMC2825543.
Copy Download .nbib Format: NLM
Share it on

Int J Cell Biol. 2010;2010:214074. doi: 10.1155/2010/214074. Epub 2010 Feb 21.

Cellular stress responses: cell survival and cell death.

International journal of cell biology

Simone Fulda, Adrienne M Gorman, Osamu Hori, Afshin Samali

Affiliations

  1. Children's Hospital, Ulm University, Eythstrasse. 24, 89075 Ulm, Germany.

PMID: 20182529 PMCID: PMC2825543 DOI: 10.1155/2010/214074

Abstract

Cells can respond to stress in various ways ranging from the activation of survival pathways to the initiation of cell death that eventually eliminates damaged cells. Whether cells mount a protective or destructive stress response depends to a large extent on the nature and duration of the stress as well as the cell type. Also, there is often the interplay between these responses that ultimately determines the fate of the stressed cell. The mechanism by which a cell dies (i.e., apoptosis, necrosis, pyroptosis, or autophagic cell death) depends on various exogenous factors as well as the cell's ability to handle the stress to which it is exposed. The implications of cellular stress responses to human physiology and diseases are manifold and will be discussed in this review in the context of some major world health issues such as diabetes, Parkinson's disease, myocardial infarction, and cancer.

References

  1. Gene Expr. 2001;9(4-5):195-201 - PubMed
  2. J Biol Chem. 2004 May 7;279(19):20108-17 - PubMed
  3. Cell. 2007 Jun 29;129(7):1337-49 - PubMed
  4. Am J Physiol Cell Physiol. 2007 Jan;292(1):C353-61 - PubMed
  5. Mol Cell. 2005 Feb 4;17(3):393-403 - PubMed
  6. Trends Cell Biol. 2001 Nov;11(11):S22-6 - PubMed
  7. Genes Dev. 2002 Jun 1;16(11):1345-55 - PubMed
  8. Proc Natl Acad Sci U S A. 1987 Mar;84(5):1404-7 - PubMed
  9. Int J Cancer. 1998 Mar 30;76(1):105-14 - PubMed
  10. Adv Exp Med Biol. 2001;500:1-10 - PubMed
  11. Cancer Res. 1999 Apr 15;59(8):1973-9 - PubMed
  12. Nat Med. 2007 May;13(5):619-24 - PubMed
  13. Science. 1997 Feb 21;275(5303):1132-6 - PubMed
  14. Circ Res. 1999 Nov 12;85(10):940-9 - PubMed
  15. J Cell Mol Med. 2007 Nov-Dec;11(6):1210-1 - PubMed
  16. Cell Mol Biol Lett. 2009;14(2):319-35 - PubMed
  17. J Neurochem. 2005 Nov;95(4):974-86 - PubMed
  18. Oncogene. 2003 Nov 24;22(53):8543-67 - PubMed
  19. Biochem Biophys Res Commun. 2007 Mar 16;354(3):707-11 - PubMed
  20. Nat Cell Biol. 2004 Dec;6(12):1221-8 - PubMed
  21. Diabetes. 2004 Sep;53(9):2271-80 - PubMed
  22. Curr Cancer Drug Targets. 2004 Nov;4(7):569-76 - PubMed
  23. Curr Opin Cell Biol. 2007 Apr;19(2):142-9 - PubMed
  24. J Biol Chem. 2003 May 23;278(21):19367-77 - PubMed
  25. Oncogene. 2003 Sep 1;22(37):5792-812 - PubMed
  26. Am J Physiol Heart Circ Physiol. 2007 Oct;293(4):H2418-28 - PubMed
  27. J Biol Chem. 2001 Sep 21;276(38):35867-74 - PubMed
  28. Front Biosci (Elite Ed). 2009 Jun 01;1:263-8 - PubMed
  29. Biochimie. 2002 Feb-Mar;84(2-3):131-41 - PubMed
  30. EMBO J. 1997 Aug 15;16(16):4887-96 - PubMed
  31. Cancer Cell. 2002 Sep;2(3):183-92 - PubMed
  32. Endocrinology. 2004 Nov;145(11):5087-96 - PubMed
  33. Cytokine Growth Factor Rev. 2008 Jun-Aug;19(3-4):325-31 - PubMed
  34. J Biol Chem. 1997 Nov 7;272(45):28191-3 - PubMed
  35. Physiol Rev. 2007 Jan;87(1):99-163 - PubMed
  36. Cancer Biol Ther. 2006 Jul;5(7):723-8 - PubMed
  37. Autophagy. 2007 Nov-Dec;3(6):561-8 - PubMed
  38. Cell. 2002 Jan 25;108(2):153-64 - PubMed
  39. Science. 2004 Jun 4;304(5676):1500-2 - PubMed
  40. Genes Cells. 2006 Oct;11(10):1161-71 - PubMed
  41. Circulation. 1996 Oct 1;94(7):1506-12 - PubMed
  42. Genes Cells. 1996 Sep;1(9):803-17 - PubMed
  43. EMBO J. 1993 May;12(5):2005-15 - PubMed
  44. J Mol Cell Cardiol. 2005 Jan;38(1):21-33 - PubMed
  45. J Neurosci. 2004 Feb 11;24(6):1486-96 - PubMed
  46. Exp Cell Res. 1999 Jun 15;249(2):396-403 - PubMed
  47. Cancer Res. 1955 Jan;15(1):1-5 - PubMed
  48. BMC Genomics. 2007 May 22;8:125 - PubMed
  49. Science. 2000 Jan 28;287(5453):664-6 - PubMed
  50. Hum Mol Genet. 2007 Jan 1;16(1):50-60 - PubMed
  51. Blood. 1998 Nov 1;92(9):3018-24 - PubMed
  52. Nat Rev Genet. 2006 Apr;7(4):306-18 - PubMed
  53. Oncogene. 2001 Sep 27;20(43):6263-8 - PubMed
  54. Cancer Biol Ther. 2006 Jul;5(7):756-9 - PubMed
  55. Science. 1997 Feb 14;275(5302):967-9 - PubMed
  56. J Neurosci Res. 2009 Jan;87(1):238-45 - PubMed
  57. Ann Med. 1999 Aug;31(4):261-71 - PubMed
  58. Nature. 2004 Nov 18;432(7015):307-15 - PubMed
  59. Vitam Horm. 2008;78:85-101 - PubMed
  60. Cell Mol Life Sci. 2006 Nov;63(22):2560-70 - PubMed
  61. Int J Biochem Cell Biol. 2006 Mar;38(3):317-32 - PubMed
  62. J Mol Cell Cardiol. 1996 Sep;28(9):2005-16 - PubMed
  63. Nat Rev Mol Cell Biol. 2007 Apr;8(4):275-83 - PubMed
  64. N Engl J Med. 1997 Apr 17;336(16):1131-41 - PubMed
  65. Biogerontology. 2002;3(4):195-206 - PubMed
  66. Diabetes. 2002 May;51(5):1618-21 - PubMed
  67. Circulation. 1999 Jun 8;99(22):2934-41 - PubMed
  68. Cell. 2006 Feb 10;124(3):587-99 - PubMed
  69. Mol Cell Biol. 2006 Jun;26(11):4257-67 - PubMed
  70. FEBS Lett. 1997 Mar 3;404(1):27-33 - PubMed
  71. Cell Death Differ. 2002 May;9(5):483-5 - PubMed
  72. Cell. 1991 Jul 26;66(2):233-43 - PubMed
  73. J Exp Med. 1999 Apr 5;189(7):1063-71 - PubMed
  74. J Neurochem. 2002 Oct;83(2):452-62 - PubMed
  75. Cell Mol Life Sci. 2008 Mar;65(6):855-61 - PubMed
  76. Cell Death Differ. 2005 Feb;12(2):162-76 - PubMed
  77. J Neurochem. 2006 Jun;97(5):1259-68 - PubMed
  78. Science. 2002 Mar 8;295(5561):1852-8 - PubMed
  79. Mol Cell Biochem. 1998 Jul;184(1-2):359-69 - PubMed
  80. FASEB J. 2001 May;15(7):1118-31 - PubMed
  81. J Insect Physiol. 1965 Feb;11:123-33 - PubMed
  82. Cell. 1993 Nov 19;75(4):641-52 - PubMed
  83. Science. 2007 Nov 9;318(5852):944-9 - PubMed
  84. Mol Cell. 2000 Dec;6(6):1355-64 - PubMed
  85. J Neurochem. 2009 May;109 Suppl 1:133-8 - PubMed
  86. Science. 2006 Aug 25;313(5790):1137-40 - PubMed
  87. J Biol Chem. 2003 Jul 25;278(30):27828-35 - PubMed
  88. Cell Biochem Biophys. 2007;48(2-3):139-46 - PubMed
  89. Cell Death Differ. 2007 Mar;14(3):400-10 - PubMed
  90. Nat Cell Biol. 2001 Sep;3(9):839-43 - PubMed
  91. Biochem J. 2007 Mar 15;402(3):581-9 - PubMed
  92. J Neurochem. 1997 May;68(5):1896-903 - PubMed
  93. Annu Rev Genet. 1988;22:631-77 - PubMed
  94. Trends Mol Med. 2006 Sep;12(9):440-50 - PubMed
  95. Cell Death Differ. 2006 May;13(5):759-72 - PubMed
  96. EMBO J. 2009 Apr 22;28(8):1111-20 - PubMed
  97. J Mol Cell Cardiol. 2006 Aug;41(2):256-64 - PubMed
  98. Oncogene. 2007 Feb 26;26(9):1324-37 - PubMed
  99. J Clin Invest. 2001 Nov;108(10):1439-50 - PubMed
  100. Expert Opin Ther Targets. 2003 Aug;7(4):559-73 - PubMed
  101. Hum Mol Genet. 2005 Sep 15;14(18):2749-55 - PubMed
  102. J Endocrinol. 2007 Aug;194(2):283-91 - PubMed
  103. Hypertension. 1999 Mar;33(3):906-13 - PubMed
  104. Diabetologia. 2006 Nov;49(11):2704-12 - PubMed
  105. Apoptosis. 2007 Sep;12(9):1543-68 - PubMed
  106. Cell Signal. 1999 Apr;11(4):239-44 - PubMed
  107. Crit Rev Biochem Mol Biol. 2009 Jun;44(2-3):98-116 - PubMed
  108. J Cell Biol. 1999 Mar 8;144(5):857-68 - PubMed
  109. Ann N Y Acad Sci. 2000;926:126-31 - PubMed
  110. Nature. 1997 Jul 31;388(6641):432-3 - PubMed
  111. Curr Opin Neurobiol. 2007 Jun;17(3):331-7 - PubMed
  112. Diabetes. 1997 Nov;46(11):1733-42 - PubMed
  113. Int Rev Cell Mol Biol. 2008;266:207-47 - PubMed
  114. J Endocrinol. 2008 Apr;197(1):139-50 - PubMed
  115. Mol Cell Biol. 2006 Nov;26(21):7999-8010 - PubMed
  116. J Cell Biol. 2004 Oct 11;167(1):27-33 - PubMed
  117. J Clin Invest. 1994 Oct;94(4):1621-8 - PubMed
  118. Nature. 2007 Jun 14;447(7146):859-63 - PubMed
  119. EMBO J. 2007 May 16;26(10):2527-39 - PubMed
  120. Cell Cycle. 2006 Nov;5(22):2592-601 - PubMed
  121. Diabetologia. 2001 Dec;44(12):2115-33 - PubMed
  122. Cell. 1996 Nov 1;87(3):391-404 - PubMed
  123. Biochim Biophys Acta. 2009 Jul;1792(7):651-63 - PubMed
  124. Blood. 2007 Jan 1;109(1):271-80 - PubMed
  125. Nature. 1988 Sep 29;335(6189):440-2 - PubMed
  126. J Cell Biochem. 2001;82(2):326-38 - PubMed
  127. Apoptosis. 2003 Jan;8(1):61-70 - PubMed
  128. J Neurosci. 2002 Dec 15;22(24):10690-8 - PubMed
  129. Annu Rev Biochem. 2005;74:739-89 - PubMed
  130. Cell Death Differ. 1995 Apr;2(2):87-96 - PubMed
  131. Cancer Res. 1992 Oct 1;52(19):5368-72 - PubMed
  132. Am J Cardiol. 1990 May 15;65(18):1261-2 - PubMed
  133. Oncogene. 1999 Jun 24;18(25):3754-60 - PubMed
  134. J Clin Invest. 2002 Feb;109(4):525-32 - PubMed
  135. Nat Rev Mol Cell Biol. 2001 Jul;2(7):545-50 - PubMed
  136. Leukemia. 1997 Apr;11 Suppl 3:380-2 - PubMed
  137. Diabetes. 2005 Apr;54(4):1074-81 - PubMed
  138. J Biol Chem. 1999 Apr 23;274(17):11549-56 - PubMed
  139. Cell Death Differ. 1999 Jun;6(6):495-6 - PubMed
  140. DNA Repair (Amst). 2004 Aug-Sep;3(8-9):1091-101 - PubMed
  141. Cell. 2009 Jun 12;137(6):1100-11 - PubMed
  142. J Insect Physiol. 1965 Jul;11(7):831-44 - PubMed
  143. Science. 2007 Feb 9;315(5813):856-9 - PubMed
  144. Nat Immunol. 2000 Dec;1(6):489-95 - PubMed
  145. J Cell Mol Med. 2008 Apr;12(2):591-606 - PubMed
  146. Diabetes. 2003 Jan;52(1):1-8 - PubMed
  147. Oncogene. 1997 Sep 18;15(12):1461-70 - PubMed
  148. Cell. 2001 Dec 28;107(7):881-91 - PubMed
  149. Oncogene. 2000 Apr 13;19(16):1975-81 - PubMed
  150. Br J Cancer. 2009 May 19;100(10):1523-9 - PubMed
  151. J Cell Mol Med. 2007 Nov-Dec;11(6):1212-3 - PubMed
  152. Nat Cell Biol. 2000 Sep;2(9):645-52 - PubMed
  153. Cell Death Differ. 2002 Sep;9(9):981-94 - PubMed
  154. J Immunol. 1995 Jan 1;154(1):363-74 - PubMed
  155. Cell. 2008 Dec 26;135(7):1311-23 - PubMed
  156. J Cell Biochem. 2002;86(2):376-93 - PubMed
  157. J Biol Chem. 2007 Apr 27;282(17):13123-32 - PubMed
  158. N Engl J Med. 1996 Oct 17;335(16):1182-9 - PubMed
  159. Proc Natl Acad Sci U S A. 1982 May;79(10):3218-22 - PubMed
  160. J Mol Cell Cardiol. 2005 Mar;38(3):517-25 - PubMed
  161. J Clin Immunol. 2003 Nov;23(6):447-59 - PubMed
  162. Am J Pathol. 1980 Feb;98(2):425-44 - PubMed
  163. J Biol Chem. 1995 Sep 8;270(36):21035-9 - PubMed
  164. Cell Stress Chaperones. 2004 Summer;9(2):122-33 - PubMed
  165. Oncogene. 2005 Feb 17;24(8):1348-58 - PubMed
  166. Nat Cell Biol. 2000 Aug;2(8):469-75 - PubMed
  167. J Biol Chem. 2003 May 9;278(19):17438-47 - PubMed
  168. Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):4838-43 - PubMed
  169. Oncogene. 2008 Oct 20;27(48):6252-75 - PubMed
  170. Cell Death Differ. 2009 Jul;16(7):1040-52 - PubMed
  171. Diabetes. 2005 Mar;54(3):657-63 - PubMed
  172. Toxicology. 2003 Nov 15;193(1-2):3-34 - PubMed
  173. Biochemistry. 2003 Mar 18;42(10):2995-3003 - PubMed
  174. CRC Crit Rev Biochem. 1985;18(3):239-80 - PubMed
  175. Hum Pathol. 2008 Jul;39(7):1042-9 - PubMed
  176. Nat Genet. 2000 Aug;25(4):406-9 - PubMed
  177. Nat Rev Mol Cell Biol. 2007 Sep;8(9):741-52 - PubMed
  178. Antioxid Redox Signal. 2008 Aug;10(8):1343-74 - PubMed
  179. Biochem Biophys Res Commun. 2005 Feb 18;327(3):801-10 - PubMed
  180. Nature. 2006 May 25;441(7092):513-7 - PubMed
  181. FEBS Lett. 1997 Jun 30;410(2-3):493-8 - PubMed
  182. J Pathol. 2001 Feb;193(2):162-8 - PubMed
  183. Biochem Soc Trans. 2006 Apr;34(Pt 2):243-6 - PubMed
  184. Cell. 2005 Sep 23;122(6):927-39 - PubMed
  185. FEBS Lett. 2007 Jul 31;581(19):3641-51 - PubMed
  186. Am J Physiol Regul Integr Comp Physiol. 2006 Sep;291(3):R566-72 - PubMed
  187. Endocr Rev. 2008 Feb;29(1):42-61 - PubMed
  188. Cancer Res. 1999 Jul 1;59(13):3068-72 - PubMed
  189. Science. 1997 Feb 21;275(5303):1129-32 - PubMed
  190. J Biol Chem. 2001 Sep 7;276(36):33915-22 - PubMed
  191. Exp Cell Res. 1995 Mar;217(1):15-21 - PubMed
  192. Mutat Res. 2003 Jun 19;527(1-2):67-80 - PubMed
  193. J Cell Mol Med. 2008 Dec;12(6A):2263-80 - PubMed
  194. Oncogene. 2002 May 13;21(21):3459-74 - PubMed
  195. Nat Cell Biol. 2000 Aug;2(8):476-83 - PubMed
  196. Mol Cell Biol. 2005 Feb;25(3):1025-40 - PubMed
  197. Circulation. 1994 Jul;90(1):556-73 - PubMed
  198. Diabetologia. 2002 Feb;45(2):174-87 - PubMed
  199. Free Radic Biol Med. 2000 Aug;29(3-4):323-33 - PubMed
  200. Autophagy. 2008 Jul;4(5):669-79 - PubMed
  201. Mol Cell. 2007 Jan 26;25(2):193-205 - PubMed
  202. Mol Cell. 2007 Dec 14;28(5):739-45 - PubMed
  203. Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):949-54 - PubMed
  204. Arterioscler Thromb Vasc Biol. 2008 Aug;28(8):1534-41 - PubMed
  205. Annu Rev Genet. 2004;38:445-76 - PubMed
  206. Nat Med. 2001 Mar;7(3):317-23 - PubMed
  207. Circulation. 1997 Jan 21;95(2):320-3 - PubMed
  208. Diabetes. 2005 Jul;54(7):2041-52 - PubMed
  209. Exp Cell Res. 2000 May 25;257(1):58-66 - PubMed
  210. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):13972-4 - PubMed
  211. Mol Cell Biol. 2001 Feb;21(4):1249-59 - PubMed
  212. Diabetologia. 2006 Jun;49(6):1229-36 - PubMed
  213. J Cell Mol Med. 2007 Nov-Dec;11(6):1214-24 - PubMed
  214. Cell Death Differ. 2008 Feb;15(2):422-5 - PubMed
  215. Cell Stress Chaperones. 1998 Dec;3(4):228-36 - PubMed
  216. Free Radic Biol Med. 1996;20(3):463-6 - PubMed
  217. EMBO J. 2007 Apr 4;26(7):1749-60 - PubMed
  218. Proc Natl Acad Sci U S A. 1990 Jan;87(2):846-50 - PubMed
  219. Cell Stress Chaperones. 2001 Jan;6(1):49-58 - PubMed
  220. Free Radic Biol Med. 2009 Sep 1;47(5):585-92 - PubMed
  221. Blood. 2003 Nov 1;102(9):3379-86 - PubMed
  222. Nature. 2000 Jan 6;403(6765):98-103 - PubMed
  223. J Clin Invest. 1999 Jan;103(1):27-37 - PubMed
  224. J Biol Chem. 2000 Apr 7;275(14):10388-93 - PubMed
  225. Neuron. 1995 Oct;15(4):961-73 - PubMed
  226. Cell. 2009 Jun 12;137(6):1112-23 - PubMed
  227. Mol Cell Biol. 2003 Oct;23(20):7198-209 - PubMed
  228. Experientia. 1996 Oct 31;52(10-11):933-41 - PubMed
  229. J Insect Physiol. 1965 Jun;11(6):803-9 - PubMed
  230. J Pathol. 1971 Sep;105(1):13-20 - PubMed
  231. Trends Pharmacol Sci. 2008 Jun;29(6):322-9 - PubMed
  232. FEBS Lett. 1999 Nov 19;461(3):306-10 - PubMed
  233. Mol Biol Cell. 1999 Nov;10(11):3787-99 - PubMed
  234. Nature. 1999 Jan 21;397(6716):271-4 - PubMed
  235. FEBS Lett. 1999 Feb 19;445(1):98-102 - PubMed
  236. J Biol Chem. 2007 Mar 9;282(10):7077-86 - PubMed
  237. Cell. 2000 Jan 7;100(1):57-70 - PubMed
  238. Br J Cancer. 1972 Aug;26(4):239-57 - PubMed
  239. J Cell Biol. 2004 May 10;165(3):347-56 - PubMed
  240. Free Radic Biol Med. 2002 Dec 15;33(12):1641-50 - PubMed
  241. Carcinogenesis. 2000 Mar;21(3):485-95 - PubMed
  242. Circ Res. 1996 Nov;79(5):949-56 - PubMed
  243. Nature. 2001 May 17;411(6835):366-74 - PubMed
  244. Diabetologia. 2005 Sep;48(9):1819-29 - PubMed
  245. J Biol Chem. 1992 Mar 15;267(8):5317-23 - PubMed
  246. Cancer Res. 1997 Jan 1;57(1):43-7 - PubMed
  247. EMBO J. 1998 Nov 2;17(21):6124-34 - PubMed
  248. Diabetes. 2003 Jan;52(1):93-101 - PubMed
  249. Annu Rev Pharmacol Toxicol. 2007;47:143-83 - PubMed
  250. J Biol Chem. 2004 Dec 3;279(49):51490-9 - PubMed
  251. Arch Biochem Biophys. 2008 Jul 15;475(2):109-14 - PubMed
  252. Science. 2009 Jul 17;325(5938):332-6 - PubMed
  253. Nat Chem Biol. 2005 Jul;1(2):112-9 - PubMed
  254. Trends Biochem Sci. 2007 Jan;32(1):37-43 - PubMed
  255. Nature. 1999 Dec 9;402(6762):672-6 - PubMed
  256. Cancer Res. 2007 Oct 15;67(20):9809-16 - PubMed
  257. J Biol Chem. 1998 Dec 11;273(50):33741-9 - PubMed
  258. Exp Cell Res. 1996 Feb 25;223(1):163-70 - PubMed
  259. Genes Dev. 2003 Jan 15;17(2):229-39 - PubMed
  260. Leukemia. 1997 Nov;11(11):1833-41 - PubMed
  261. J Cell Mol Med. 2005 Jul-Sep;9(3):609-22 - PubMed
  262. J Neurochem. 2007 Mar;100(6):1449-57 - PubMed
  263. Trends Biochem Sci. 2005 Mar;30(3):151-9 - PubMed
  264. Mol Cancer Res. 2006 Jul;4(7):423-36 - PubMed
  265. Cell. 2005 Jan 28;120(2):237-48 - PubMed
  266. J Clin Invest. 1997 Apr 1;99(7):1645-50 - PubMed
  267. Antioxid Redox Signal. 2005 Mar-Apr;7(3-4):497-507 - PubMed
  268. J Biol Chem. 2005 Dec 23;280(51):41827-34 - PubMed
  269. Cell Signal. 2007 Sep;19(9):1807-19 - PubMed
  270. J Cereb Blood Flow Metab. 2008 Sep;28(9):1564-73 - PubMed
  271. Science. 1989 Jul 21;245(4915):301-5 - PubMed
  272. Mol Cell Biol. 2006 Dec;26(24):9220-31 - PubMed
  273. Nat Rev Mol Cell Biol. 2007 Jul;8(7):519-29 - PubMed
  274. EMBO J. 2000 Nov 1;19(21):5720-8 - PubMed
  275. J Cell Mol Med. 2007 Mar-Apr;11(2):239-51 - PubMed
  276. Nat Rev Mol Cell Biol. 2001 Mar;2(3):211-6 - PubMed
  277. Cell Stress Chaperones. 2004 Autumn;9(3):265-75 - PubMed
  278. Cell Cycle. 2008 Jun 1;7(11):1511-21 - PubMed
  279. Carcinogenesis. 2002 May;23(5):687-96 - PubMed
  280. J Biol Chem. 1998 Mar 27;273(13):7523-8 - PubMed
  281. Trends Neurosci. 2007 May;30(5):244-50 - PubMed
  282. Int J Cancer. 1995 Jul 4;62(1):107-14 - PubMed
  283. J Biol Chem. 2004 Jun 11;279(24):25497-502 - PubMed
  284. Circ Res. 2000 Nov 10;87(10):856-64 - PubMed
  285. Proc Natl Acad Sci U S A. 1977 Sep;74(9):3840-4 - PubMed
  286. Curr Mol Med. 2008 May;8(3):207-20 - PubMed
  287. J Biol Chem. 2002 Jun 14;277(24):21836-42 - PubMed
  288. Biochem Biophys Res Commun. 1999 Feb 5;255(1):6-11 - PubMed
  289. J Clin Invest. 2001 May;107(10):1263-73 - PubMed
  290. Biochim Biophys Acta. 2009 May;1787(5):414-20 - PubMed
  291. FASEB J. 2002 Feb;16(2):135-46 - PubMed
  292. Nature. 1990 Nov 22;348(6299):334-6 - PubMed
  293. Mol Cell Biol. 2000 Sep;20(18):6826-36 - PubMed
  294. Cell Death Differ. 2008 Feb;15(2):364-75 - PubMed
  295. Autophagy. 2007 Jul-Aug;3(4):374-6 - PubMed
  296. J Biol Chem. 2000 Feb 18;275(7):5131-5 - PubMed
  297. Nature. 2002 Jan 3;415(6867):92-6 - PubMed
  298. Mol Cell Biol. 2006 Aug;26(15):5688-97 - PubMed
  299. J Biol Chem. 2003 Dec 19;278(51):51613-21 - PubMed
  300. Cell. 1996 Oct 18;87(2):171 - PubMed
  301. Cancer Lett. 2009 Aug 28;281(2):128-33 - PubMed
  302. J Biol Chem. 2000 Aug 18;275(33):25665-71 - PubMed
  303. Nat Chem Biol. 2008 May;4(5):313-21 - PubMed
  304. Genes Dev. 2004 Jun 1;18(11):1272-82 - PubMed
  305. Lab Invest. 1962 Nov;11:986-1015 - PubMed
  306. Expert Rev Neurother. 2007 Aug;7(8):957-60 - PubMed
  307. Annu Rev Biochem. 1986;55:1151-91 - PubMed
  308. Mol Cell. 2001 Jun;7(6):1153-63 - PubMed
  309. Diabetes. 2005 Dec;54 Suppl 2:S97-107 - PubMed
  310. Blood. 1997 Dec 1;90(11):4266-70 - PubMed
  311. EXS. 1996;77:139-63 - PubMed
  312. Mol Cell Biol. 1997 Sep;17(9):5317-27 - PubMed
  313. EMBO J. 1999 Nov 1;18(21):5943-52 - PubMed
  314. J Neuropathol Exp Neurol. 2008 Mar;67(3):200-11 - PubMed
  315. Diabetologia. 2005 Aug;48(8):1541-8 - PubMed
  316. Parkinsonism Relat Disord. 2005 Jun;11 Suppl 1:S3-7 - PubMed
  317. EMBO Rep. 2006 Sep;7(9):880-5 - PubMed
  318. Nat Cell Biol. 2005 Feb;7(2):186-94 - PubMed

Publication Types