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Mikesch JH, Gronemeyer H, So CW. Discovery of novel transcriptional and epigenetic targets in APL by global ChIP analyses: Emerging opportunity and challenge. Cancer Cell. 2010;17(2):112-4doi: 10.1016/j.ccr.2010.01.012.
Mikesch, J. H., Gronemeyer, H., & So, C. W. (2010). Discovery of novel transcriptional and epigenetic targets in APL by global ChIP analyses: Emerging opportunity and challenge. Cancer cell, 17(2), 112-4. https://doi.org/10.1016/j.ccr.2010.01.012
Mikesch, Jan-Henrik, et al. "Discovery of novel transcriptional and epigenetic targets in APL by global ChIP analyses: Emerging opportunity and challenge." Cancer cell vol. 17,2 (2010): 112-4. doi: https://doi.org/10.1016/j.ccr.2010.01.012
Mikesch JH, Gronemeyer H, So CW. Discovery of novel transcriptional and epigenetic targets in APL by global ChIP analyses: Emerging opportunity and challenge. Cancer Cell. 2010 Feb 17;17(2):112-4. doi: 10.1016/j.ccr.2010.01.012. PMID: 20159604.
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Cancer Cell. 2010 Feb 17;17(2):112-4. doi: 10.1016/j.ccr.2010.01.012.

Discovery of novel transcriptional and epigenetic targets in APL by global ChIP analyses: Emerging opportunity and challenge.

Cancer cell

Jan-Henrik Mikesch, Hinrich Gronemeyer, Chi Wai Eric So

Affiliations

  1. Department of Haematological Medicine, King's College London, UK.

PMID: 20159604 DOI: 10.1016/j.ccr.2010.01.012

Abstract

Identifying transcriptional program(s) deregulated by oncoproteins is key to understanding the molecular basis of the disease. In this issue of Cancer Cell, two studies by Martens et al. and Wang et al. provide global blueprints for transcriptional targets and epigenetic modifications mediated by PML-RARalpha in acute promyelocytic leukemia.

2010 Elsevier Inc. All rights reserved.

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