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Froud K, Titone D, Marantz A, et al. Brain/behavior Asymmetry in Schizophrenia: A MEG Study of Cross-modal Semantic Priming. J Neurolinguistics. 2010;23(3):223-239doi: 10.1016/j.jneuroling.2009.03.001.
Froud, K., Titone, D., Marantz, A., & Levy, D. L. (2010). Brain/behavior Asymmetry in Schizophrenia: A MEG Study of Cross-modal Semantic Priming. Journal of neurolinguistics, 23(3), 223-239. https://doi.org/10.1016/j.jneuroling.2009.03.001
Froud, Karen, et al. "Brain/behavior Asymmetry in Schizophrenia: A MEG Study of Cross-modal Semantic Priming." Journal of neurolinguistics vol. 23,3 (2010): 223-239. doi: https://doi.org/10.1016/j.jneuroling.2009.03.001
Froud K, Titone D, Marantz A, Levy DL. Brain/behavior Asymmetry in Schizophrenia: A MEG Study of Cross-modal Semantic Priming. J Neurolinguistics. 2010 May 01;23(3):223-239. doi: 10.1016/j.jneuroling.2009.03.001. PMID: 20396647; PMCID: PMC2852879.
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J Neurolinguistics. 2010 May 01;23(3):223-239. doi: 10.1016/j.jneuroling.2009.03.001.

Brain/behavior Asymmetry in Schizophrenia: A MEG Study of Cross-modal Semantic Priming.

Journal of neurolinguistics

Karen Froud, Debra Titone, Alec Marantz, Deborah L Levy

Affiliations

  1. Department of Biobehavioral Sciences, Teachers College, Columbia University, New York NY 10027.

PMID: 20396647 PMCID: PMC2852879 DOI: 10.1016/j.jneuroling.2009.03.001

Abstract

Semantic priming has long been used to investigate how concepts and ideas are related at the level of language, and has become a convenient tool for assessing conceptual and semantic dysfunction in cognitive disorders, including schizophrenia. The study of semantic priming in schizophrenia has led to diverse results: enhanced priming, reduced priming, and priming equivalent to that found in nonpsychiatric comparison groups. A number of hypotheses have been proposed to explain some of the observed deficits in schizophrenia patients. For example, difficulties in word recognition may be due to hyperactivation of too many lexical representations or to a failure to inhibit lexical competitors. One way to distinguish between these possible explanations is to move beyond reliance on behavior alone and to examine the neural processes involved in lexical recognition. Here we present a magnetoencephalographic study of semantic priming in schizophrenia. Importantly, schizophrenia patients and healthy controls did not differ in performance on a priming task. We show that normal behavioral performance can occur in a context of aberrant neural responses. These findings suggest that normal behavioral responses in schizophrenia can be achieved through neural mechanisms that differ from those seen in the psychiatrically well brain.

References

  1. Schizophr Res. 2003 Feb 1;59(2-3):181-6 - PubMed
  2. Schizophr Bull. 1986;12(3):394-407 - PubMed
  3. Schizophr Res. 1988 Jan-Feb;1(1):61-6 - PubMed
  4. Schizophr Res. 2005 Oct 15;78(2-3):285-91 - PubMed
  5. J Abnorm Psychol. 2000 Nov;109(4):761-7 - PubMed
  6. Int J Lang Commun Disord. 1998;33 Suppl:202-7 - PubMed
  7. Neuroimage. 2003 Dec;20(4):1923-33 - PubMed
  8. Arch Gen Psychiatry. 1987 Jan;44(1):13-20 - PubMed
  9. Schizophr Res. 2004 May 1;68(1):75-85 - PubMed
  10. Psychiatry Res. 2004 May 30;126(3):241-52 - PubMed
  11. Schizophr Bull. 1986;12(3):360-71 - PubMed
  12. J Int Neuropsychol Soc. 2002 Nov;8(7):884-92 - PubMed
  13. J Abnorm Psychol. 2006 May;115(2):251-65 - PubMed
  14. Psychopathology. 2001 Mar-Apr;34(2):75-80 - PubMed
  15. J Abnorm Psychol. 2002 May;111(2):313-20 - PubMed
  16. Schizophr Res. 2005 Dec 15;80(2-3):173-83 - PubMed
  17. Schizophr Res. 1997 Feb 7;23(2):147-65 - PubMed
  18. Am J Psychiatry. 1997 May;154(5):640-6 - PubMed
  19. Biol Psychiatry. 1997 Jul 1;42(1):13-23 - PubMed
  20. Schizophr Res. 1995 Aug 15;16(3):217-24 - PubMed
  21. Science. 1980 Jan 11;207(4427):203-5 - PubMed
  22. Behav Res Methods Instrum Comput. 2004 Aug;36(3):481-7 - PubMed
  23. Trends Cogn Sci. 2003 May;7(5):187-189 - PubMed
  24. Psychophysiology. 2007 Nov;44(6):991-1001 - PubMed
  25. Neuropsychology. 1997 Oct;11(4):506-13 - PubMed
  26. Schizophr Res. 1992 Dec;8(2):171-81 - PubMed
  27. Arch Gen Psychiatry. 1976 Jun;33(6):766-71 - PubMed
  28. J Exp Psychol Learn Mem Cogn. 2005 Nov;31(6):1385-1397 - PubMed
  29. Brain. 2005 May;128(Pt 5):963-78 - PubMed
  30. Psychol Med. 1997 Nov;27(6):1295-302 - PubMed
  31. Neurosci Biobehav Rev. 2007;31(4):465-84 - PubMed
  32. Schizophr Res. 2007 Jan;89(1-3):198-210 - PubMed
  33. J Int Neuropsychol Soc. 2002 Jul;8(5):699-720 - PubMed
  34. Schizophr Res. 2006 Jun;84(2-3):272-80 - PubMed
  35. Psychiatry Res. 2002 Oct 1;115(3):137-53 - PubMed
  36. Brain Lang. 2004 Jul-Sep;90(1-3):88-94 - PubMed
  37. Arch Gen Psychiatry. 1982 Aug;39(8):879-83 - PubMed
  38. Biol Psychiatry. 1999 Jul 1;46(1):137-40 - PubMed
  39. Am J Psychiatry. 2008 Jan;165(1):74-81 - PubMed
  40. Psychophysiology. 2000 Jul;37(4):456-63 - PubMed
  41. Am J Psychiatry. 2005 Dec;162(12):2233-45 - PubMed
  42. Arch Gen Psychiatry. 2002 Jul;59(7):641-8 - PubMed
  43. Brain Res Cogn Brain Res. 2001 Jan;10(3):345-8 - PubMed
  44. Brain Lang. 2002 Apr-Jun;81(1-3):666-78 - PubMed
  45. Psychophysiology. 2002 Nov;39(6):851-60 - PubMed
  46. Br J Psychiatry. 2008 Feb;192(2):92-7 - PubMed
  47. Biol Psychiatry. 1993 Dec 15;34(12):864-77 - PubMed
  48. J Abnorm Psychol. 1996 Nov;105(4):592-601 - PubMed
  49. Schizophr Res. 1992 Mar;6(3):251-5 - PubMed
  50. Psychol Bull. 1992 Jul;112(1):155-9 - PubMed
  51. J Abnorm Psychol. 1990 Aug;99(3):215-21 - PubMed

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