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Klein LJ, Visser FC. The effect of insulin on the heart : Part 1: Effects on metabolism and function. Neth Heart J. 2010;18(4):197-201doi: 10.1007/BF03091761.
Klein, L. J., & Visser, F. C. (2010). The effect of insulin on the heart : Part 1: Effects on metabolism and function. Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 18(4), 197-201. https://doi.org/10.1007/BF03091761
Klein, L J, and Visser, F C. "The effect of insulin on the heart : Part 1: Effects on metabolism and function." Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation vol. 18,4 (2010): 197-201. doi: https://doi.org/10.1007/BF03091761
Klein LJ, Visser FC. The effect of insulin on the heart : Part 1: Effects on metabolism and function. Neth Heart J. 2010 Apr;18(4):197-201. doi: 10.1007/BF03091761. PMID: 20428418; PMCID: PMC2856868.
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Neth Heart J. 2010 Apr;18(4):197-201. doi: 10.1007/BF03091761.

The effect of insulin on the heart : Part 1: Effects on metabolism and function.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

L J Klein, F C Visser

Affiliations

  1. Department of Cardiology, VU Medical Centre, Amsterdam, the Netherlands.

PMID: 20428418 PMCID: PMC2856868 DOI: 10.1007/BF03091761

Abstract

Positive inotropic effects of insulin were described early after the isolation of insulin from the pancreas but data on the effect of insulin on the heart are conflicting. Systemic insulin administration results in a reduction in circulating free fatty acids and an improvement in myocardial glucose uptake, which causes an efficiency improvement in the myocardial cell. There is strong evidence that insulin administration results in functional improvement in dysfunctional myocardium. (Neth Heart J 2010;18:197-201.).

Keywords: Heart; Heart Failure; Insulin; Metabolism; Ventribular Function

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