Neurochem Int. 1985;7(6):1073-8. doi: 10.1016/0197-0186(85)90157-3.
Neurochemistry international
M V Mikaelyan, R M Nalbandyan
PMID: 20493021 DOI: 10.1016/0197-0186(85)90157-3
The copper-containing protein, neurocuprein, has been obtained in a highly purified state from human brain. Many similarities in properties of neurocupreins from human and bovine brains are noted. These concern molecular weights, copper contents, isoelectric points, amino acid compositions, optical and EPR spectra as well as their reaction with catecholamines. However, it was found that the content of neurocuprein in the whole human brain is significantly (by a factor 2.5-3.0) higher than in bovine brain.