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Cell Metab. 2010 Jun 09;11(6):451-2. doi: 10.1016/j.cmet.2010.05.009.

Chronic kidney disease and GWAS: "the proper study of mankind is man".

Cell metabolism

Peter M Price, Kurt Hirschhorn, Robert L Safirstein

Affiliations

  1. Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

PMID: 20519117 DOI: 10.1016/j.cmet.2010.05.009

Abstract

Genome-wide association studies (GWAS) have been applied to complex diseases such as diabetes and hypertension, successfully uncovering strong gene associations of potential pathophysiologic significance. Recently, two studies (Köttgen et al., 2010; Chambers et al., 2010) have been applied to uncover genes relevant to the pathophysiology of chronic kidney disease (CKD).

Copyright 2010 Elsevier Inc. All rights reserved.

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