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Hayne OA. Screening tests of the hemostatic system. Can Fam Physician. 1976;22:33-5
Hayne, O. A. (1976). Screening tests of the hemostatic system. Canadian family physician Medecin de famille canadien, 2233-5.
Hayne, O A. "Screening tests of the hemostatic system." Canadian family physician Medecin de famille canadien vol. 22 (1976): 33-5.
Hayne OA. Screening tests of the hemostatic system. Can Fam Physician. 1976 Dec;22:33-5. PMID: 20469270; PMCID: PMC2378355.
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Can Fam Physician. 1976 Dec;22:33-5.

Screening tests of the hemostatic system.

Canadian family physician Medecin de famille canadien

O A Hayne

PMID: 20469270 PMCID: PMC2378355

Abstract

The hemostatic system consists of the subcutaneous tissue/vessel wall/platelet system and the coagulation cascade. Hemostasis occurs initially through the interaction between circulating platelets and subendothelial collagen, so that a platelet plug is formed. The platelet plug produces hemostasis, but is unstable and will disintegrate unless the coagulation cascade generates fibrin. The presence of the fibrin in the plug results in permanent hemostasis. The five tests of hemostasis - platelet count, bleeding time, partial thromboplastin time, prothrombin time and Factor XIII assay - are described.

References

  1. Prog Hematol. 1971;7:185-234 - PubMed
  2. Prog Hemost Thromb. 1972;1:1-37 - PubMed
  3. Prog Hemost Thromb. 1974;2(0):249-71 - PubMed

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