Display options
Share it on

Can Fam Physician. 1977 Dec;23:60-8.

The prevention of rh-immunization.

Canadian family physician Medecin de famille canadien

J M Bowman

PMID: 20469282 PMCID: PMC2379019

Abstract

Administration of Rh immune globulin to the Rh-negative unimmunized woman at risk of Rh-immunization is highly effective if given in sufficient dose prior to active Rh-immunization. Remaining problems are: 1. treating all of those at risk, 2. protecting those who abort, 3. treating after amniocentesis, 4. instituting an antenatal prophylaxis program to protect the 1.8 percent immunized too early to be protected by post-delivery injection of Rh immune globulin, 5. protecting those who have had massive transplacental fetal hemorrhages. All physicians practicing obstetrics should ensure that all of their unimmunized Rh-negative women are protected against Rh-immunization.

References

  1. Klin Wochenschr. 1957 Jun 15;35(12):637-8 - PubMed
  2. Can Med Assoc J. 1967 Nov 18;97(21):1245-57 - PubMed
  3. Br Med J. 1961 May 27;1(5238):1486-90 - PubMed
  4. Transfusion. 1971 Nov-Dec;11(6):333-9 - PubMed
  5. Lancet. 1954 Jun 12;266(6824):1213-5 - PubMed
  6. Pediatr Res. 1976 Apr;10(4):213-5 - PubMed
  7. Presse Med. 1970 Nov 7;78(47):2072 - PubMed
  8. Immunology. 1975 Feb;28(2):349-57 - PubMed
  9. Vox Sang. 1973 Oct;25(4):308-16 - PubMed
  10. Am J Obstet Gynecol. 1968 Feb 15;100(4):567-9 - PubMed
  11. Science. 1946 May 10;103(2680):583-4 - PubMed
  12. Transfusion. 1964 Jan-Feb;4:26-32 - PubMed

Publication Types