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Sirsi S, Borden M. Microbubble Compositions, Properties and Biomedical Applications. Bubble Sci Eng Technol. 2009;1(1):3-17doi: 10.1179/175889709X446507.
Sirsi, S., & Borden, M. (2009). Microbubble Compositions, Properties and Biomedical Applications. Bubble science engineering and technology, 1(1), 3-17. https://doi.org/10.1179/175889709X446507
Sirsi, Shashank, and Borden, Mark. "Microbubble Compositions, Properties and Biomedical Applications." Bubble science engineering and technology vol. 1,1 (2009): 3-17. doi: https://doi.org/10.1179/175889709X446507
Sirsi S, Borden M. Microbubble Compositions, Properties and Biomedical Applications. Bubble Sci Eng Technol. 2009 Nov;1(1):3-17. doi: 10.1179/175889709X446507. PMID: 20574549; PMCID: PMC2889676.
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Bubble Sci Eng Technol. 2009 Nov;1(1):3-17. doi: 10.1179/175889709X446507.

Microbubble Compositions, Properties and Biomedical Applications.

Bubble science engineering and technology

Shashank Sirsi, Mark Borden

Affiliations

  1. Department of Chemical Engineering, Columbia University, 500 W 120 ST, New York, NY 10027.

PMID: 20574549 PMCID: PMC2889676 DOI: 10.1179/175889709X446507

Abstract

Over the last decade, there has been significant progress towards the development of microbubbles as theranostics for a wide variety of biomedical applications. The unique ability of microbubbles to respond to ultrasound makes them useful agents for contrast ultrasound imaging, molecular imaging, and targeted drug and gene delivery. The general composition of a microbubble is a gas core stabilized by a shell comprised of proteins, lipids or polymers. Each type of microbubble has its own unique advantages and can be tailored for specialized functions. In this review, different microbubbles compositions and physiochemical properties are discussed in the context of current progress towards developing novel constructs for biomedical applications, with specific emphasis on molecular imaging and targeted drug/gene delivery.

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