Display options
Share it on

Addict Biol. 2000 Jul 01;5(3):261-8. doi: 10.1111/j.1369-1600.2000.tb00190.x.

Risk factors for alcoholic liver disease.

Addiction biology

S Bellentani, G Saccoccio, F Masutti, M Giacca, L Miglioli, A Monzoni, C Tiribelli

Affiliations

  1. Fondo per lo Studio delle Malattie del Fegato, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy ICGEB, AREA Ricerca, Padriciano, Trieste, Italy.

PMID: 20575840 DOI: 10.1111/j.1369-1600.2000.tb00190.x

Abstract

Abstract Alcoholic liver disease (ALD) is still a frequent disorder, even though its incidence appears to be decreasing. In spite of intense investigation, the precise mechanisms leading to ALD are still imprecisely known. This is due in part to the lack of a reliable animal model; in part to the difficulty of obtaining clinical data of adequate sample size and derived from unblased populations and finally from the lack of uniformity of the criteria used to define ALD. This paper will review what is known of the various pieces of this puzzle, with particular emphasis not only on the total amount of alcohol consumed, but also on drinking patterns and type of alcoholic beverage ingested. The other potential factors such as age, gender, genetic background, nutritional status, occupational hazards and viral diseases (especially HCV infection) will be touched upon.

Publication Types