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Case Rep Med. 2010;2010:819242. doi: 10.1155/2010/819242. Epub 2010 Jul 04.

Pulmonary alveolar microlithiasis: a case report with emphasis on imaging findings.

Case reports in medicine

Guilherme Abdalla, Edson Marchiori, Gláucia Zanetti, Antonio Mucillo, Mariana Leite Pereira, Nina Ventura, Pedro Martins, Carolina Pesce Lamas Constantino, Rodrigo Canellas, Viviane Brandão, Romulo Varella de Oliveira

Affiliations

  1. Department of Radiology, Rio de Janeiro Federal University, CEP 21941.913, Rio de Janeiro, Brazil.

PMID: 20671919 PMCID: PMC2910500 DOI: 10.1155/2010/819242

Abstract

Pulmonary alveolar microlithiasis (PAM) is a rare disease characterized by the presence of small calculi in the alveolar space. The authors report a case of a 21-year-old man with a 2-year history of shortness of breath on exertion and dry cough. Physical examination was altered only for crackles at auscultation. Pulmonary function revealed a mild restrictive ventilatory defect and the chest radiograph demonstrated paracardiac confluence of dense micronodular infiltrate. High-resolution CT scan revealed diffuse ground glass attenuation and septal thickening, more pronounced in lower pulmonary regions, with calcifications along the interlobar septa and subpleural regions. A transbronchial lung biopsy confirmed the diagnosis of PAM.

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