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Rossetto A, Baccarani U, Lorenzin D, et al. Disseminate fungal infection after acute pancreatitis in a simultaneous pancreas-kidney recipient. J Transplant. 2010;2010:898245doi: 10.1155/2010/898245.
Rossetto, A., Baccarani, U., Lorenzin, D., Risaliti, A., Viale, P., Bresadola, V., & Adani, G. L. (2010). Disseminate fungal infection after acute pancreatitis in a simultaneous pancreas-kidney recipient. Journal of transplantation, 2010898245. https://doi.org/10.1155/2010/898245
Rossetto, Anna, et al. "Disseminate fungal infection after acute pancreatitis in a simultaneous pancreas-kidney recipient." Journal of transplantation vol. 2010 (2010): 898245. doi: https://doi.org/10.1155/2010/898245
Rossetto A, Baccarani U, Lorenzin D, Risaliti A, Viale P, Bresadola V, Adani GL. Disseminate fungal infection after acute pancreatitis in a simultaneous pancreas-kidney recipient. J Transplant. 2010;2010:898245. doi: 10.1155/2010/898245. Epub 2010 Jun 07. PMID: 20628506; PMCID: PMC2902020.
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J Transplant. 2010;2010:898245. doi: 10.1155/2010/898245. Epub 2010 Jun 07.

Disseminate fungal infection after acute pancreatitis in a simultaneous pancreas-kidney recipient.

Journal of transplantation

Anna Rossetto, Umberto Baccarani, Dario Lorenzin, Andrea Risaliti, Pierluigi Viale, Vittorio Bresadola, Gian Luigi Adani

Affiliations

  1. Department of Surgery & Transplantation, University Hospital of Udine, 33100 Udine, Italy.

PMID: 20628506 PMCID: PMC2902020 DOI: 10.1155/2010/898245

Abstract

Fungal infections after kidney transplantation are a major cause of morbidity and mortality, and Candida infection of the pancreas is considered an infrequent but important agent in necrotizing pancreatitis. We report the case of a 43-year-old Caucasian patient who underwent simultaneous pancreas-kidney transplantation because of diabetes type I, and chronic renal failure with peritoneal dialysis. The postoperative course was complicated by acute pancreatitis due to the thrombosis of the splenic artery of the graft, the subsequent acute rupture of the external iliac artery caused by fungal arteritis (Candida glabrata), and peritonitis a few days later caused by sigmoid perforation with detection of Candida glabrata infection of the resected intestinal tract. The present case remarks that awareness and prevention of fungal infection are major issues in the transplant field. Important information can be added by systematic culture of conservation perfusates but, probably, the best way for early recognition of a critical level of infectious risk remains the routine application of the colonization index screening. In cases of positive results, preemptive antifungal therapy could be warranted.

References

  1. Clin Infect Dis. 2004 Jan 15;38(2):161-89 - PubMed
  2. Transpl Int. 2005 Jun;18(6):643-50 - PubMed
  3. Lancet. 1989 Dec 16;2(8677):1437-40 - PubMed
  4. Clin Infect Dis. 2001 Jun 15;32(12):1713-7 - PubMed
  5. Am J Gastroenterol. 2005 Jul;100(7):1620 - PubMed
  6. Ann Surg. 1994 Dec;220(6):751-8 - PubMed
  7. Clin Infect Dis. 2009 Jan 15;48(2):194-202 - PubMed
  8. N Engl J Med. 1998 Jun 11;338(24):1741-51 - PubMed
  9. Transplant Proc. 2009 May;41(4):1189-90 - PubMed
  10. Surg Today. 2007;37(3):207-11 - PubMed
  11. Transpl Int. 2001 Dec;14(6):438-41 - PubMed
  12. Transplantation. 2003 Jul 15;76(1):266-9 - PubMed
  13. Mycoses. 2006 Jul;49(4):340-2 - PubMed

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