Display options
Cite
Golukhova EZ, Polunina AG, Zhuravleva SV, et al. Size of left cardiac chambers correlates with cerebral microembolic load in open heart operations. Cardiol Res Pract. 2010;2010:143679doi: 10.4061/2010/143679.
Golukhova, E. Z., Polunina, A. G., Zhuravleva, S. V., Lefterova, N. P., & Begachev, A. V. (2010). Size of left cardiac chambers correlates with cerebral microembolic load in open heart operations. Cardiology research and practice, 2010143679. https://doi.org/10.4061/2010/143679
Golukhova, Elena Z, et al. "Size of left cardiac chambers correlates with cerebral microembolic load in open heart operations." Cardiology research and practice vol. 2010 (2010): 143679. doi: https://doi.org/10.4061/2010/143679
Golukhova EZ, Polunina AG, Zhuravleva SV, Lefterova NP, Begachev AV. Size of left cardiac chambers correlates with cerebral microembolic load in open heart operations. Cardiol Res Pract. 2010;2010:143679. doi: 10.4061/2010/143679. Epub 2010 Jun 13. PMID: 20631826; PMCID: PMC2901602.
Copy Download .nbib Format: NLM
Share it on

Cardiol Res Pract. 2010;2010:143679. doi: 10.4061/2010/143679. Epub 2010 Jun 13.

Size of left cardiac chambers correlates with cerebral microembolic load in open heart operations.

Cardiology research and practice

Elena Z Golukhova, Anna G Polunina, Svetlana V Zhuravleva, Natalia P Lefterova, Alexey V Begachev

Affiliations

  1. A. N. Bakulev Scientific Center of Cardiovascular Surgery, Russian Academy of Medical Sciences, Moscow 119571, Russia.

PMID: 20631826 PMCID: PMC2901602 DOI: 10.4061/2010/143679

Abstract

Background. Microemboli are a widely recognized etiological factor of cerebral complications in cardiac surgery patients. The present study was aimed to determine if size of left cardiac chambers relates to cerebral microembolic load in open heart operations. Methods. Thirty patients participated in the study. Echocardiography was performed in 2-3 days before surgery. A transcranial Doppler system was used for registering intraoperative microemboli. Results. Preoperative left atrium and left ventricular end-systolic and end-diastolic sizes significantly correlated with intraoperative microembolic load (rs = 0.48, 0.57 and 0.53, Ps < .01, resp.). The associations between left ventricular diameters and number of cerebral microemboli remained significant when cardiopulmonary bypass time was included as a covariate into the analysis. Conclusions. The present results demonstrate that increased size of left heart chambers is an influential risk factor for elevated cerebral microembolic load during open heart operations. Mini-invasive surgery and carbon dioxide insufflation into wound cavity may be considered as neuroprotective approaches in patients with high risk of cerebral microembolism.

References

  1. Semin Cardiothorac Vasc Anesth. 2005 Jun;9(2):123-9 - PubMed
  2. J Cardiothorac Vasc Anesth. 2003 Jun;17(3):329-35 - PubMed
  3. Ann Thorac Surg. 1999 Jul;68(1):89-93 - PubMed
  4. Anesthesiology. 2007 Jan;106(1):164-77 - PubMed
  5. J Thorac Cardiovasc Surg. 1995 Feb;109(2):249-57; discussion 257-8 - PubMed
  6. Stroke. 1998 Nov;29(11):2396-403 - PubMed
  7. Perfusion. 2005 Jan;20(1):3-10 - PubMed
  8. J Thorac Cardiovasc Surg. 2004 Jan;127(1):51-6 - PubMed
  9. J Thorac Cardiovasc Surg. 2004 Jan;127(1):57-64 - PubMed
  10. Anesth Analg. 2006 Nov;103(5):1089-93 - PubMed
  11. Anesth Analg. 2008 Jan;106(1):24-31, table of contents - PubMed
  12. Chest. 2001 Jan;119(1):25-30 - PubMed
  13. Perfusion. 2009 Nov;24(6):409-15 - PubMed
  14. Ann Thorac Surg. 2009 Jul;88(1):349-50; author reply 350-1 - PubMed
  15. J Thorac Cardiovasc Surg. 2004 Jun;127(6):1759-65 - PubMed
  16. Cerebrovasc Dis. 2007;23(1):50-6 - PubMed
  17. J Appl Physiol Respir Environ Exerc Physiol. 1979 Sep;47(3):537-43 - PubMed
  18. Med Sci Monit. 2003 Oct;9(10):CR411-6 - PubMed
  19. Ann Thorac Surg. 2008 Feb;85(2):543-7 - PubMed

Publication Types