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Nano Lett. 2010 Oct 13;10(10):3899-903. doi: 10.1021/nl101586s.

Nanoelectromechanical resonator arrays for ultrafast, gas-phase chromatographic chemical analysis.

Nano letters

Mo Li, E B Myers, H X Tang, S J Aldridge, H C McCaig, J J Whiting, R J Simonson, N S Lewis, M L Roukes

Affiliations

  1. Kavli Nanoscience Institute, California Institute of Technology, MS 114-36, Pasadena, California 91125.
  2. Department of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125.
  3. Sandia National Laboratories, Albuquerque, New Mexico 87123.

PMID: 20795729 PMCID: PMC3839305 DOI: 10.1021/nl101586s

Abstract

Miniaturized gas chromatography (GC) systems can provide fast, quantitative analysis of chemical vapors in an ultrasmall package. We describe a chemical sensor technology based on resonant nanoelectromechanical systems (NEMS) mass detectors that provides the speed, sensitivity, specificity, and size required by the microscale GC paradigm. Such NEMS sensors have demonstrated detection of subparts per billion (ppb) concentrations of a phosphonate analyte. By combining two channels of NEMS detection with an ultrafast GC front-end, chromatographic analysis of 13 chemicals was performed within a 5 s time window.

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