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Al-Yamany M, Terbrugge KG, Willinsky R, et al. Palliative embolisation of brain arteriovenous malformations presenting with progressive neurological deficit. Interv Neuroradiol. 2001;6(3):177-83doi: 10.1177/159101990000600302.
Al-Yamany, M., Terbrugge, K. G., Willinsky, R., Montanera, W., Tymianski, M., & Wallace, M. C. (2000). Palliative embolisation of brain arteriovenous malformations presenting with progressive neurological deficit. Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 6(3), 177-83. https://doi.org/10.1177/159101990000600302
Al-Yamany, M, et al. "Palliative embolisation of brain arteriovenous malformations presenting with progressive neurological deficit." Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences vol. 6,3 (2000): 177-83. doi: https://doi.org/10.1177/159101990000600302
Al-Yamany M, Terbrugge KG, Willinsky R, Montanera W, Tymianski M, Wallace MC. Palliative embolisation of brain arteriovenous malformations presenting with progressive neurological deficit. Interv Neuroradiol. 2000 Sep 30;6(3):177-83. doi: 10.1177/159101990000600302. Epub 2001 May 15. PMID: 20667196; PMCID: PMC3679675.
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Interv Neuroradiol. 2000 Sep 30;6(3):177-83. doi: 10.1177/159101990000600302. Epub 2001 May 15.

Palliative embolisation of brain arteriovenous malformations presenting with progressive neurological deficit.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences

M Al-Yamany, K G Terbrugge, R Willinsky, W Montanera, M Tymianski, M C Wallace

Affiliations

  1. Radiology and Surgery, University of Toronto, Head Division of Interventional and Diagnostic Neuroradiology, The Western Hospital, University Health Network,Toronto, Ontario, Canada - [email protected].

PMID: 20667196 PMCID: PMC3679675 DOI: 10.1177/159101990000600302

Abstract

SUMMARY: Large arteriovenous malformations (AVMs) located in eloquent areas of the brain are generally considered incurable because of the high morbidity and mortality associated with their treatment. When these patients develop a progressive neurological deficit they in time often become severely disabled. This report presents the results of palliative embolisation in this subgroup of patients. Analysis of our data-base of 714 patients with known brain AVMs revealed 17 patients who presented with progressive neurological deficit and who underwent palliative embolisation as the therapeutic modality of choice for management of their AVM. One patient was excluded due to lack of follow-up and two were excluded because they later received radiation therapy. Following embolisation 43% had improvement of their neurological deficit, 50% stabilized and 7% continued to deteriorate and these clinical results persisted for an average of more than 2 years follow-up. Transient neurological morbidity associated with embolisation treatment was 7% and there was no permanent morbidity and no mortality. Palliative embolisation of brain AVMs presenting with progressive neurological deficits arrested deterioration in more than 90% of patients and was associated with low morbidity and no mortality.

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