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Vet Med Int. 2010;2010:953272. doi: 10.4061/2010/953272. Epub 2010 Jun 16.

Feline T-Cell Receptor gamma V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats.

Veterinary medicine international

Alexander Thomas Andreas Weiss, Werner Hecht, Manfred Reinacher

Affiliations

  1. Institute of Veterinary Pathology, University of Giessen, Frankfurter Strasse 96, 35392 Giessen, Germany.

PMID: 20634910 PMCID: PMC2904447 DOI: 10.4061/2010/953272

Abstract

The variable domains of antigen receptors are very diverse and assembled in a modular system from a number of V-, D-, and J-region genes. Here we describe additional variants of V- and J-region genes of the feline T-cell receptor gamma (TRG) as well as the corresponding RSSs retrieved from Trace Archive of feline genomic sequences. Additionally, an unusually recombined TRGV-domain containing a partial inverted repeat of the included J-region and a short interspersed element of the CAN-SINE family located within the feline T-cell receptor gamma locus are also described.

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