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Pulkkinen L, Ukkola O, Kolehmainen M, et al. Ghrelin in diabetes and metabolic syndrome. Int J Pept. 2010;2010doi: 10.1155/2010/248948.
Pulkkinen, L., Ukkola, O., Kolehmainen, M., & Uusitupa, M. (2010). Ghrelin in diabetes and metabolic syndrome. International journal of peptides, 2010. https://doi.org/10.1155/2010/248948
Pulkkinen, Leena, et al. "Ghrelin in diabetes and metabolic syndrome." International journal of peptides vol. 2010 (2010). doi: https://doi.org/10.1155/2010/248948
Pulkkinen L, Ukkola O, Kolehmainen M, Uusitupa M. Ghrelin in diabetes and metabolic syndrome. Int J Pept. 2010;2010. doi: 10.1155/2010/248948. Epub 2010 Apr 27. PMID: 20700400; PMCID: PMC2911592.
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Int J Pept. 2010;2010. doi: 10.1155/2010/248948. Epub 2010 Apr 27.

Ghrelin in diabetes and metabolic syndrome.

International journal of peptides

Leena Pulkkinen, Olavi Ukkola, Marjukka Kolehmainen, Matti Uusitupa

Affiliations

  1. Department of Clinical Nutrition, Food and Health Research Centre, University of Eastern Finland, Kuopio Campus, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Campus P.O. Box 1627 FI-70211 Kuopio, Finland.

PMID: 20700400 PMCID: PMC2911592 DOI: 10.1155/2010/248948

Abstract

Metabolic syndrome is a cluster of related risk factors for cardiovascular disease, type 2 diabetes and liver disease. Obesity, which has become a global public health problem, is one of the major risk factors for development of metabolic syndrome and type 2 diabetes. Obesity is a complex disease, caused by the interplay between environmental and genetic factors. Ghrelin is one of the circulating peptides, which stimulates appetite and regulates energy balance, and thus is one of the candidate genes for obesity and T2DM. During the last years both basic research and genetic association studies have revealed association between the ghrelin gene and obesity, metabolic syndrome or type 2 diabetes.

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