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Emer JJ, Spear JB. Primary cutaneous blastomycosis as a cause of acute respiratory distress syndrom: case report and literature review. J Clin Aesthet Dermatol. 2009;2(3):22-30
Emer, J. J., & Spear, J. B. (2009). Primary cutaneous blastomycosis as a cause of acute respiratory distress syndrom: case report and literature review. The Journal of clinical and aesthetic dermatology, 2(3), 22-30.
Emer, Jason J, and Spear, Joel B. "Primary cutaneous blastomycosis as a cause of acute respiratory distress syndrom: case report and literature review." The Journal of clinical and aesthetic dermatology vol. 2,3 (2009): 22-30.
Emer JJ, Spear JB. Primary cutaneous blastomycosis as a cause of acute respiratory distress syndrom: case report and literature review. J Clin Aesthet Dermatol. 2009 Mar;2(3):22-30. PMID: 20729940; PMCID: PMC2923955.
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J Clin Aesthet Dermatol. 2009 Mar;2(3):22-30.

Primary cutaneous blastomycosis as a cause of acute respiratory distress syndrom: case report and literature review.

The Journal of clinical and aesthetic dermatology

Jason J Emer, Joel B Spear

PMID: 20729940 PMCID: PMC2923955

Abstract

Blastomycosis is a fungal infection caused by Blastomyces dermatitidis. Exposure in endemic regions frequently occurs when spores in soil are disturbed and subsequently inhaled. Less commonly, primary cutaneous blastomycosis may follow after traumatic inoculation of the fungus into the skin. Most patients infected with blastomycosis are asymptomatic, but an unfortunate small number present with fulminant disease. Rarely, the infection can affect organs, such as the skin, bone, or genitourinary system. In a small percentage of cases, blastomycosis may cause acute respiratory distress syndrome, which is associated with a very high mortality rate. Increased survival rates have been shown when the clinician has a high index of suspicion and facilitates rapid evaluation and initiation of the appropriate therapy. We present a rare case of a patient presenting with primary cutaneous blastomycosis that progressed to disseminated disease causing acute respiratory distress syndrome. High clinical suspicion, prompt diagnostic testing, and therapy with amphotericin B, confirmed the diagnosis and resulted in a swift recovery.

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