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Zuercher M, Ewy GA, Otto CW, et al. Gasping in response to basic resuscitation efforts: observation in a Swine model of cardiac arrest. Crit Care Res Pract. 2010;2010doi: 10.1155/2010/351638.
Zuercher, M., Ewy, G. A., Otto, C. W., Hilwig, R. W., Bobrow, B. J., Clark, L., Chikani, V., Sanders, A. B., Berg, R. A., & Kern, K. B. (2010). Gasping in response to basic resuscitation efforts: observation in a Swine model of cardiac arrest. Critical care research and practice, 2010. https://doi.org/10.1155/2010/351638
Zuercher, Mathias, et al. "Gasping in response to basic resuscitation efforts: observation in a Swine model of cardiac arrest." Critical care research and practice vol. 2010 (2010). doi: https://doi.org/10.1155/2010/351638
Zuercher M, Ewy GA, Otto CW, Hilwig RW, Bobrow BJ, Clark L, Chikani V, Sanders AB, Berg RA, Kern KB. Gasping in response to basic resuscitation efforts: observation in a Swine model of cardiac arrest. Crit Care Res Pract. 2010;2010. doi: 10.1155/2010/351638. Epub 2010 May 31. PMID: 20948884; PMCID: PMC2951081.
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Crit Care Res Pract. 2010;2010. doi: 10.1155/2010/351638. Epub 2010 May 31.

Gasping in response to basic resuscitation efforts: observation in a Swine model of cardiac arrest.

Critical care research and practice

Mathias Zuercher, Gordon A Ewy, Charles W Otto, Ronald W Hilwig, Bentley J Bobrow, Lani Clark, Vatsal Chikani, Arthur B Sanders, Robert A Berg, Karl B Kern

Affiliations

  1. Department of Anaesthesia, University Hospital Basel, CH 4031, Basel, Switzerland.

PMID: 20948884 PMCID: PMC2951081 DOI: 10.1155/2010/351638

Abstract

Objective. To analyze the effect of basic resuscitation efforts on gasping and of gasping on survival. Methods. This is secondary analysis of a previously reported study comparing continuous chest compressions (CCC CPR) versus chest compressions plus ventilation (30:2 CPR) on survival. 64 swine were randomized to 1 of these 2 basic CPR approaches after either short (3 or 4 minutes) or long (5 or 6 minutes) durations of untreated VF. At 12 minutes of VF, all received the same Guidelines 2005 Advanced Cardiac Life Support. Neurologically status was evaluated at 24 hours. A score of 1 is normal, 2 is abnormal, such as not eating or drinking normally, unsteady gait, or slight resistance to restraint, 3 severely abnormal, where the animal is recumbent and unable to stand, 4 is comatose, and 5 is dead. For this analysis a neurological outcome score of 1 or 2 was classified as "good", and a score of 3, 4, or 5 was classified as "poor." Results. Gasping was more likely to continue or if absent, to resume in the animals with short durations of untreated VF before basic resuscitation efforts. With long durations of untreated VF, the frequency of gasping and survival was better in swine receiving CCC CPR. In the absence of frequent gasping, intact survival was rare in the long duration of untreated VF group. Conclusions. Gasping is an important phenomenon during basic resuscitation efforts for VF arrest and in this model was more frequent with CCC-CPR.

References

  1. J Appl Physiol (1985). 1988 Dec;65(6):2641-7 - PubMed
  2. Chest. 1995 Sep;108(3):821-7 - PubMed
  3. Circulation. 1993 Oct;88(4 Pt 1):1907-15 - PubMed
  4. Pediatr Res. 2006 Aug;60(2):174-9 - PubMed
  5. Circulation. 2007 Nov 27;116(22):2525-30 - PubMed
  6. Ann Emerg Med. 1992 Dec;21(12):1464-7 - PubMed
  7. Biol Neonate. 1996;70(5):280-8 - PubMed
  8. Circulation. 1997 Mar 18;95(6):1635-41 - PubMed
  9. Crit Care Med. 1994 May;22(5):879-83 - PubMed
  10. Ann Emerg Med. 1995 Sep;26(3):342-50 - PubMed
  11. Resuscitation. 2000 Jun;45(1):7-15 - PubMed
  12. J Appl Physiol. 1973 Apr;34(4):549-58 - PubMed
  13. Resuscitation. 2006 May;69(2):329-34 - PubMed
  14. Crit Care Med. 2006 Dec;34(12 Suppl):S438-41 - PubMed
  15. Am J Respir Crit Care Med. 1994 Dec;150(6 Pt 1):1709-13 - PubMed
  16. Resuscitation. 2007 Nov;75(2):366-71 - PubMed
  17. Circulation. 2008 Dec 9;118(24):2550-4 - PubMed
  18. Respir Physiol Neurobiol. 2003 Apr 15;135(1):97-101 - PubMed
  19. Crit Care Med. 2004 Jan;32(1):238-40 - PubMed
  20. Am J Respir Crit Care Med. 1994 Sep;150(3):861-4 - PubMed

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