Display options
Cite
Mason SE, McShane R, Ritchie CW. Diagnostic tests for Alzheimer's disease: rationale, methodology, and challenges. Int J Alzheimers Dis. 2010;2010doi: 10.4061/2010/972685.
Mason, S. E., McShane, R., & Ritchie, C. W. (2010). Diagnostic tests for Alzheimer's disease: rationale, methodology, and challenges. International journal of Alzheimer's disease, 2010. https://doi.org/10.4061/2010/972685
Mason, S E, et al. "Diagnostic tests for Alzheimer's disease: rationale, methodology, and challenges." International journal of Alzheimer's disease vol. 2010 (2010). doi: https://doi.org/10.4061/2010/972685
Mason SE, McShane R, Ritchie CW. Diagnostic tests for Alzheimer's disease: rationale, methodology, and challenges. Int J Alzheimers Dis. 2010 Aug 08;2010. doi: 10.4061/2010/972685. PMID: 20811564; PMCID: PMC2929623.
Copy Download .nbib Format: NLM
Share it on

Int J Alzheimers Dis. 2010 Aug 08;2010. doi: 10.4061/2010/972685.

Diagnostic tests for Alzheimer's disease: rationale, methodology, and challenges.

International journal of Alzheimer's disease

S E Mason, R McShane, C W Ritchie

Affiliations

  1. Centre of Mental Health, Imperial College London, London W6 8LN, UK.

PMID: 20811564 PMCID: PMC2929623 DOI: 10.4061/2010/972685

Abstract

There has been a large increase in the amount of research seeking to define or diagnose Alzheimer's disease before patients develop dementia. If successful, this would principally have clinical benefits both in terms of treatment as well as risk modification. Moreover, a better method for diagnosing predementia disease would assist research which seeks to develop such treatments and risk modification strategies. The evidence-based definition of a diagnostic test's accuracy is fundamental to achieve the above goals and to address this, the Cochrane Collaboration has established a Diagnostic Test Accuracy group dedicated to examining the utility and accuracy of proposed tests in dementia and cognitive impairment. We present here the assumptions and observations underpinning the chosen methodology as well as the initial methodological approach decided upon.

References

  1. Biol Psychiatry. 2008 Nov 15;64(10):871-9 - PubMed
  2. Neurology. 1991 Apr;41(4):479-86 - PubMed
  3. Lancet Neurol. 2008 Sep;7(9):779-86 - PubMed
  4. JAMA. 2003 May 28;289(20):2651-62 - PubMed
  5. Lancet Neurol. 2009 Sep;8(9):791-801 - PubMed
  6. Neurology. 1984 Jul;34(7):939-44 - PubMed
  7. JAMA. 1998 Mar 4;279(9):688-95 - PubMed
  8. Arch Neurol. 2009 Oct;66(10):1210-5 - PubMed
  9. Arch Neurol. 1985 Nov;42(11):1097-105 - PubMed
  10. JAMA. 2002 Aug 21;288(7):872-81 - PubMed
  11. J Am Geriatr Soc. 2008 Aug;56(8):1424-33 - PubMed
  12. Dement Geriatr Cogn Disord. 1998 Jul-Aug;9(4):219-26 - PubMed
  13. Neurobiol Aging. 1997 Jul-Aug;18(4 Suppl):S1-2 - PubMed
  14. Lancet Neurol. 2007 Aug;6(8):734-46 - PubMed
  15. Arch Gen Psychiatry. 2006 Aug;63(8):916-24 - PubMed
  16. Mult Scler. 2009 Dec;15(12):1528-31 - PubMed

Publication Types