Display options
Cite
Olivot JM, Albers GW. Using advanced MRI techniques for patient selection before acute stroke therapy. Curr Treat Options Cardiovasc Med. 2010;12(3):230-9doi: 10.1007/s11936-010-0072-y.
Olivot, J. M., & Albers, G. W. (2010). Using advanced MRI techniques for patient selection before acute stroke therapy. Current treatment options in cardiovascular medicine, 12(3), 230-9. https://doi.org/10.1007/s11936-010-0072-y
Olivot, Jean-Marc, and Albers, Gregory W. "Using advanced MRI techniques for patient selection before acute stroke therapy." Current treatment options in cardiovascular medicine vol. 12,3 (2010): 230-9. doi: https://doi.org/10.1007/s11936-010-0072-y
Olivot JM, Albers GW. Using advanced MRI techniques for patient selection before acute stroke therapy. Curr Treat Options Cardiovasc Med. 2010 Jun;12(3):230-9. doi: 10.1007/s11936-010-0072-y. PMID: 20842546.
Copy Download .nbib Format: NLM
Share it on

Curr Treat Options Cardiovasc Med. 2010 Jun;12(3):230-9. doi: 10.1007/s11936-010-0072-y.

Using advanced MRI techniques for patient selection before acute stroke therapy.

Current treatment options in cardiovascular medicine

Jean-Marc Olivot, Gregory W Albers

Affiliations

  1. Department of Neurology and Neurological Sciences and the Stanford Stroke Center, Stanford University Medical Center, 701 Welch Road, Suite 325, Palo Alto, CA, 94304, USA.

PMID: 20842546 DOI: 10.1007/s11936-010-0072-y

Abstract

OPINION STATEMENT: Results of acute MRI studies may help guide the management of acute stroke. Patients with a malignant MRI pattern may be poor candidates for reperfusion therapies yet may benefit from hemicraniectomy. Preliminary data suggest that patients with a carefully identified diffusion weighted imaging (DWI)/perfusion weighted imaging (PWI) mismatch may benefit from intravenous recombinant tissue plasminogen activator in a 3- to 6-hour time window; however, confirmatory studies with larger sample sizes are required before clinical use of this strategy can be generally recommended. Post hoc analyses of recent studies suggest that PWI techniques that use a threshold to exclude benign oligemia from penumbra and DWI techniques that use apparent diffusion coefficient thresholds to exclude reversible DWI lesions to distinguish the ischemic core from penumbra appear to provide more accurate determinations of the volume of salvageable tissue. New automated software programs are now implementing these techniques to generate quantitative PWI and DWI maps within minutes. Prospective trials are in progress to investigate these new techniques. The results of these studies will further refine the application of MRI to select patients for acute recanalization therapies.

References

  1. Ann Neurol. 1996 Aug;40(2):216-26 - PubMed
  2. Stroke. 2009 Jun;40(6):2046-54 - PubMed
  3. Ann Neurol. 2000 Apr;47(4):462-9 - PubMed
  4. Stroke. 2000 Sep;31(9):2175-81 - PubMed
  5. Stroke. 2009 Aug;40(8):2910 - PubMed
  6. Lancet Neurol. 2009 Feb;8(2):141-50 - PubMed
  7. Stroke. 2006 May;37(5):1227-31 - PubMed
  8. Stroke. 2007 Mar;38(3):1036-43 - PubMed
  9. Stroke. 2006 Jul;37(7):1741-8 - PubMed
  10. Neurology. 2009 Mar 31;72(13):1140-5 - PubMed
  11. Ann Neurol. 2008 Jan;63(1):52-60 - PubMed
  12. Stroke. 1981 Nov-Dec;12(6):723-5 - PubMed
  13. J Cereb Blood Flow Metab. 2008 May;28(5):887-91 - PubMed
  14. Stroke. 2008 Aug;39(8):2257-63 - PubMed
  15. Radiology. 2008 Nov;249(2):614-23 - PubMed
  16. Stroke. 2009 Jun;40(6):2055-61 - PubMed
  17. Radiology. 1990 Aug;176(2):439-45 - PubMed
  18. J Cereb Blood Flow Metab. 1994 Sep;14(5):723-31 - PubMed
  19. Neurology. 2006 Sep 12;67(5):824-9 - PubMed
  20. Ann Neurol. 2006 Nov;60(5):508-17 - PubMed
  21. Stroke. 2009 Feb;40(2):469-75 - PubMed
  22. J Neurol Neurosurg Psychiatry. 2009 Sep;80(9):991-6 - PubMed
  23. Lancet. 2007 Jan 27;369(9558):293-8 - PubMed
  24. Magn Reson Imaging. 1995;13(1):73-80 - PubMed
  25. Stroke. 2009 May;40(5):1692-7 - PubMed
  26. Lancet Neurol. 2008 Apr;7(4):299-309 - PubMed
  27. N Engl J Med. 1995 Dec 14;333(24):1581-7 - PubMed
  28. Stroke. 2005 Jan;36(1):66-73 - PubMed
  29. Stroke. 2008 Mar;39(3):870-7 - PubMed
  30. Lancet Neurol. 2007 Mar;6(3):215-22 - PubMed
  31. J Cereb Blood Flow Metab. 2007 Feb;27(2):404-13 - PubMed
  32. Stroke. 2007 Dec;38(12):3158-64 - PubMed
  33. Lancet Neurol. 2008 Mar;7(3):256-67 - PubMed
  34. Stroke. 2009 Oct;40(10):3245-51 - PubMed
  35. AJNR Am J Neuroradiol. 1990 May;11(3):423-9 - PubMed
  36. Stroke. 2009 Aug;40(8):2743-8 - PubMed
  37. Ann Neurol. 2005 Sep;58(3):462-5 - PubMed
  38. J Magn Reson Imaging. 2009 Oct;30(4):743-52 - PubMed
  39. N Engl J Med. 2008 Sep 25;359(13):1317-29 - PubMed

Publication Types