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Zeng LY, Cai C. A domino synthesis of benzoquinolinamide in the presence of iodine. Org Biomol Chem. 2010;8(21):4803-5doi: 10.1039/c0ob00364f.
Zeng, L. Y., & Cai, C. (2010). A domino synthesis of benzoquinolinamide in the presence of iodine. Organic & biomolecular chemistry, 8(21), 4803-5. https://doi.org/10.1039/c0ob00364f
Zeng, Li-Yan, and Cai, Chun. "A domino synthesis of benzoquinolinamide in the presence of iodine." Organic & biomolecular chemistry vol. 8,21 (2010): 4803-5. doi: https://doi.org/10.1039/c0ob00364f
Zeng LY, Cai C. A domino synthesis of benzoquinolinamide in the presence of iodine. Org Biomol Chem. 2010 Nov 07;8(21):4803-5. doi: 10.1039/c0ob00364f. Epub 2010 Sep 06. PMID: 20820665.
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Org Biomol Chem. 2010 Nov 07;8(21):4803-5. doi: 10.1039/c0ob00364f. Epub 2010 Sep 06.

A domino synthesis of benzoquinolinamide in the presence of iodine.

Organic & biomolecular chemistry

Li-Yan Zeng, Chun Cai

Affiliations

  1. Chemical Engineering College, Nanjing University of Science and Technology, Nanjing, 210094, China.

PMID: 20820665 DOI: 10.1039/c0ob00364f

Abstract

The domino synthesis of benzo[f]quinolinyl and benzo[h]quinolinyl acetamides from diketene, amines, aromatic aldehydes and naphthalenamine was developed, and the catalyst iodine was found to be crucial to the reaction. The structure was deduced from the mass spectrum, (1)H NMR, (13)C NMR spectrum and 2D NMR performed on two representative products.

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