Curr Oncol. 2010 Sep;17:S38-44. doi: 10.3747/co.v17i0.698.
Current oncology (Toronto, Ont.)
H Quon, D A Loblaw
PMID: 20882131 PMCID: PMC2935708 DOI: 10.3747/co.v17i0.698
The discovery of androgen deprivation therapy (ADT) has been one of the most important advances in the treatment of prostate cancer. Here, the indications for the use of ADT are reviewed, together with the data supporting each indication. The settings for ADT use include cytoreduction; combined ADT and radiotherapy; pathologic node-positive disease; and recurrent, metastatic, or progressive prostate cancer.
Keywords: Androgen antagonists; combined-modality therapy; disease progression; hormonal anti-neoplastic agents; orchiectomy; prostatectomy; prostatic neoplasms; radiotherapy