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West J Emerg Med. 2010 May;11(2):186-8.

Catatonia associated with initiating paliperidone treatment.

The western journal of emergency medicine

Nathanael J McKeown, James H Bryan, B Zane Horowitz

Affiliations

  1. Oregon Health & Science University, Department of Emergency Medicine, Oregon Poison Control Center, Portland VA.

PMID: 20823970 PMCID: PMC2908655

Abstract

We present a case of catatonia, which occurred shortly after starting a new antipsychotic, paliperidone, an active metabolite of risperidone. Catatonia may be caused by a variety of conditions, including metabolic, neurologic, psychiatric and toxic processes. Interestingly, risperidone, which has been thought to cause several cases of catatonia, has also been recommended as a potential treatment. We discuss potential mechanisms for causes of drug-induced catatonia as well as potential treatment options.

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