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Open Rheumatol J. 2010 Aug 26;4:28-30. doi: 10.2174/1874312901004010028.

Prevalence of anticardiolipin antibodies in pregnancies with history of repeated miscarriages.

The open rheumatology journal

Ligia Cosentino Junqueira Franco Spegiorin, Eloísa A Galão, Lúcia Buchalla Bagarelli, Antonio Hélio Oliani, José Maria Pereira de Godoy

Affiliations

  1. Department of Gynecology of São José do Rio Preto Medicine School of São Paulo (FAMERP), Brazil.

PMID: 20890453 PMCID: PMC2948133 DOI: 10.2174/1874312901004010028

Abstract

AIM: This study aimed at evaluating the prevalence of high anticardiolipin antibody and lupus anticoagulant levels in women with histories of at least two miscarriages.

METHODS: The presence of high anticardiolipin antibody and lupus anticoagulant levels were evaluated in 52 patients with ages between 17 and 41 (mean 26.7 years old) who had histories of repeated miscarriages.

RESULTS: High anticardiolipin antibody levels were identified in 55.77% and lupus anticoagulant levels in 2% of the individuals.

CONCLUSION: In conclusion, women who suffer from repeated miscarriages present with a high prevalence of anticardiolipin antibodies. Further studies on this issue are crucial as these antibodies are associated with hypercoagulability and thus increased the risk of thromboembolic events.

Keywords: Repetitive miscarriage; anticardiolipin antibodies; anticoagulant.; lupus; thromboembolism

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