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Backer V, Rasmussen LM. Exercise-Induced Asthma Symptoms and Nighttime Asthma: Are They Similar to AHR?. J Allergy (Cairo). 2009;2009:378245doi: 10.1155/2009/378245.
Backer, V., & Rasmussen, L. M. (2009). Exercise-Induced Asthma Symptoms and Nighttime Asthma: Are They Similar to AHR?. Journal of allergy, 2009378245. https://doi.org/10.1155/2009/378245
Backer, V, and Rasmussen, L M. "Exercise-Induced Asthma Symptoms and Nighttime Asthma: Are They Similar to AHR?." Journal of allergy vol. 2009 (2009): 378245. doi: https://doi.org/10.1155/2009/378245
Backer V, Rasmussen LM. Exercise-Induced Asthma Symptoms and Nighttime Asthma: Are They Similar to AHR?. J Allergy (Cairo). 2009;2009:378245. doi: 10.1155/2009/378245. Epub 2009 Nov 12. PMID: 20975796; PMCID: PMC2958256.
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J Allergy (Cairo). 2009;2009:378245. doi: 10.1155/2009/378245. Epub 2009 Nov 12.

Exercise-Induced Asthma Symptoms and Nighttime Asthma: Are They Similar to AHR?.

Journal of allergy

V Backer, L M Rasmussen

Affiliations

  1. Department of Respiratory Medicine, Bispebjerg Hospital, University of Copenhagen, 2400 Copenhagen NV, Denmark.

PMID: 20975796 PMCID: PMC2958256 DOI: 10.1155/2009/378245

Abstract

Background. Asthma experienced during exercise and during the night is based on the presence of airway hyperresponsiveness (AHR). The aim of the present study was to examine whether AHR is a predictor of exercise-induced asthma (EIA) and nighttime symptoms. Material. We included 793 asthmatics subjects with symptoms and a positive asthma test. Results. Mean (SD) FEV1 was 93% (15), 71% had rhinitis, and 62% had atopy. Both EIA and nighttime symptoms were associated with AHR; however, when including other factors of importance in a multivariate analysis, logRDR was eliminated, whereas FEV1% pred (P < .001), smoking (P < .05), atopy (P < .001), sex (P < .001), and treatment (P < .01) were associated with having EIA while dyspnoea (P < .001), cough (P < .001), and eosinophils (P < .01) were associated with frequent night symptoms. The risk of having nighttime awakenings due to asthma was more than twofold higher among those with EIA symptoms than among those without symptoms (OR (CI95%) 2.77 (2.0-3.8) (P < .001)). In Conclusion. EIA and night symptoms are associated with AHR, but other factors of importance eliminated this close association. Night asthma is more closely associated with airway inflammation than AHR.

References

  1. Chest. 2006 Sep;130(3):929; author reply 929 - PubMed
  2. Chest. 2004 Mar;125(3):909-15 - PubMed
  3. Br J Gen Pract. 2004 Mar;54(500):201-6 - PubMed
  4. J Allergy Clin Immunol. 2008 Aug;122(2):254-60, 260.e1-7 - PubMed
  5. Bull Eur Physiopathol Respir. 1983 Jan-Feb;19(1):43-9 - PubMed
  6. Curr Opin Allergy Clin Immunol. 2006 Feb;6(1):37-42 - PubMed
  7. Clin Exp Allergy. 2007 Nov;37(11):1594-601 - PubMed
  8. Respir Med. 2006 Feb;100(2):354-62 - PubMed
  9. Am J Respir Crit Care Med. 2003 Feb 15;167(4):534-7 - PubMed
  10. Am J Rhinol. 2005 Nov-Dec;19(6):591-8 - PubMed
  11. Am Rev Respir Dis. 1987 Dec;136(6):1412-7 - PubMed
  12. Thorax. 2002 Mar;57(3):226-30 - PubMed
  13. J Allergy Clin Immunol. 2008 Aug;122(2):238-46; quiz 247-8 - PubMed
  14. Clin Respir J. 2007 Jul;1(1):3-15 - PubMed
  15. Eur Respir J. 2006 Jun;27(6):1144-51 - PubMed
  16. Clin Exp Allergy. 2000 Jun;30 Suppl 1:2-5 - PubMed
  17. Curr Allergy Asthma Rep. 2005 Mar;5(2):116-22 - PubMed
  18. Eur Respir J. 2008 Jan;31(1):143-78 - PubMed
  19. Clin Rev Allergy Immunol. 2006 Oct-Dec;31(2-3):163-80 - PubMed
  20. Respir Med. 2005 Dec;99(12):1576-82 - PubMed
  21. Scand J Med Sci Sports. 2009 Apr;19(2):174-8 - PubMed
  22. Allergy. 2008 Apr;63 Suppl 86:8-160 - PubMed
  23. J Allergy Clin Immunol. 1991 Jul;88(1):68-76 - PubMed
  24. Am Rev Respir Dis. 1987 Jul;136(1):225-44 - PubMed
  25. Thorax. 1983 Oct;38(10):760-5 - PubMed
  26. Ann Allergy Asthma Immunol. 2007 Jan;98(1):44-50 - PubMed
  27. Am J Respir Crit Care Med. 2007 Apr 15;175(8):783-90 - PubMed
  28. Clin Exp Allergy. 1992 Aug;22(8):741-7 - PubMed
  29. Allergy. 1987 Feb;42(2):109-16 - PubMed
  30. Thorax. 2007 Dec;62(12):1034-6 - PubMed
  31. Treat Respir Med. 2004;3(6):365-79 - PubMed
  32. Chest. 2008 Oct;134(4):733-739 - PubMed
  33. Sports Med. 1986 Mar-Apr;3(2):136-50 - PubMed
  34. J Allergy Clin Immunol. 2005 Jun;115(6):1137-42 - PubMed

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