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López San Román A, Van Domselaar M, Rivero M, et al. Complete remission of a primary rectal lymphoma on ulcerative colitis, after withdrawal of azathioprine and infliximab. J Crohns Colitis. 2008;2(1):93-6doi: 10.1016/j.crohns.2007.10.005.
López San Román, A., Van Domselaar, M., Rivero, M., Redondo, C., Arribas, R., & Rey, A. (2008). Complete remission of a primary rectal lymphoma on ulcerative colitis, after withdrawal of azathioprine and infliximab. Journal of Crohn's & colitis, 2(1), 93-6. https://doi.org/10.1016/j.crohns.2007.10.005
López San Román, Antonio, et al. "Complete remission of a primary rectal lymphoma on ulcerative colitis, after withdrawal of azathioprine and infliximab." Journal of Crohn's & colitis vol. 2,1 (2008): 93-6. doi: https://doi.org/10.1016/j.crohns.2007.10.005
López San Román A, Van Domselaar M, Rivero M, Redondo C, Arribas R, Rey A. Complete remission of a primary rectal lymphoma on ulcerative colitis, after withdrawal of azathioprine and infliximab. J Crohns Colitis. 2008 Mar;2(1):93-6. doi: 10.1016/j.crohns.2007.10.005. PMID: 21172197.
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J Crohns Colitis. 2008 Mar;2(1):93-6. doi: 10.1016/j.crohns.2007.10.005.

Complete remission of a primary rectal lymphoma on ulcerative colitis, after withdrawal of azathioprine and infliximab.

Journal of Crohn's & colitis

Antonio López San Román, Manuel Van Domselaar, Miguel Rivero, Clara Redondo, Rosario Arribas, Antonio Rey

Affiliations

  1. Gastroenterology, Units, Hospital "Ramón y Cajal", 28034 Madrid, Spain.

PMID: 21172197 DOI: 10.1016/j.crohns.2007.10.005

Abstract

A 45-year-old woman was diagnosed with ulcerative colitis and treated with mesalazine, prednisone and, finally, azathioprine and infliximab. Colonoscopy revealed a rectal ulcer, identified by biopsy as a large cell B-lymphoma, positive for leukocyte common antigen (LCA), CD 20 and LMP-1 and negative for CD 3. Three months after withdrawal of all immunosuppressors, a proctocolectomy was performed. The resection specimen contained an area of B-cell polymorphic hyperplasia, but no residual tumour. The patient remains well after 2 years of follow-up, without any further antineoplastic therapy.

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