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Kong F, Zhu J, Wu J, et al. dbCRID: a database of chromosomal rearrangements in human diseases. Nucleic Acids Res. 2010;39:D895-900doi: 10.1093/nar/gkq1038.
Kong, F., Zhu, J., Wu, J., Peng, J., Wang, Y., Wang, Q., Fu, S., Yuan, L. L., & Li, T. (2011). dbCRID: a database of chromosomal rearrangements in human diseases. Nucleic acids research, 39D895-900. https://doi.org/10.1093/nar/gkq1038
Kong, Fanlou, et al. "dbCRID: a database of chromosomal rearrangements in human diseases." Nucleic acids research vol. 39 (2011): D895-900. doi: https://doi.org/10.1093/nar/gkq1038
Kong F, Zhu J, Wu J, Peng J, Wang Y, Wang Q, Fu S, Yuan LL, Li T. dbCRID: a database of chromosomal rearrangements in human diseases. Nucleic Acids Res. 2011 Jan;39:D895-900. doi: 10.1093/nar/gkq1038. Epub 2010 Nov 04. PMID: 21051346; PMCID: PMC3013658.
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Nucleic Acids Res. 2011 Jan;39:D895-900. doi: 10.1093/nar/gkq1038. Epub 2010 Nov 04.

dbCRID: a database of chromosomal rearrangements in human diseases.

Nucleic acids research

Fanlou Kong, Jing Zhu, Jun Wu, Jianjian Peng, Ying Wang, Qing Wang, Songbin Fu, Li-Lian Yuan, Tongbin Li

Affiliations

  1. Biolead.org Research Group, LC Sciences, Houston, TX 77054, USA.

PMID: 21051346 PMCID: PMC3013658 DOI: 10.1093/nar/gkq1038

Abstract

Chromosomal rearrangement (CR) events result from abnormal breaking and rejoining of the DNA molecules, or from crossing-over between repetitive DNA sequences, and they are involved in many tumor and non-tumor diseases. Investigations of disease-associated CR events can not only lead to important discoveries about DNA breakage and repair mechanisms, but also offer important clues about the pathologic causes and the diagnostic/therapeutic targets of these diseases. We have developed a database of Chromosomal Rearrangements In Diseases (dbCRID, http://dbCRID.biolead.org), a comprehensive database of human CR events and their associated diseases. For each reported CR event, dbCRID documents the type of the event, the disease or symptoms associated, and--when possible--detailed information about the CR event including precise breakpoint positions, junction sequences, genes and gene regions disrupted and experimental techniques applied to discover/analyze the CR event. With 2643 records of disease-associated CR events curated from 1172 original studies, dbCRID is a comprehensive and dynamic resource useful for studying DNA breakage and repair mechanisms, and for analyzing the genetic basis of human tumor and non-tumor diseases.

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