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Munro CA. Fungal echinocandin resistance. F1000 Biol Rep. 2010;2:66doi: 10.3410/B2-66.
Munro, C. A. (2010). Fungal echinocandin resistance. F1000 biology reports, 266. https://doi.org/10.3410/B2-66
Munro, Carol A. "Fungal echinocandin resistance." F1000 biology reports vol. 2 (2010): 66. doi: https://doi.org/10.3410/B2-66
Munro CA. Fungal echinocandin resistance. F1000 Biol Rep. 2010 Sep 08;2:66. doi: 10.3410/B2-66. PMID: 21173867; PMCID: PMC2990507.
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F1000 Biol Rep. 2010 Sep 08;2:66. doi: 10.3410/B2-66.

Fungal echinocandin resistance.

F1000 biology reports

Carol A Munro

Affiliations

  1. Aberdeen Fungal Group, School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen Foresterhill, Aberdeen, AB25 2ZD UK.

PMID: 21173867 PMCID: PMC2990507 DOI: 10.3410/B2-66

Abstract

Echinocandins are the most recent introduction to the antifungal armamentarium and target the synthesis of β-(1,3)-glucan, the major structural polysaccharide of the fungal cell wall. Mechanisms have been identified that reduce the efficacy of the echinocandins: mutations of the Fks subunit of the target enzyme complex or a compensatory increase in the production of chitin, the second structural cell wall polysaccharide.

References

  1. Drug Resist Updat. 2007 Jun;10(3):121-30 - PubMed
  2. Antimicrob Agents Chemother. 2008 Jul;52(7):2305-12 - PubMed
  3. Antimicrob Agents Chemother. 2006 Aug;50(8):2719-27 - PubMed
  4. PLoS Pathog. 2009 Jul;5(7):e1000532 - PubMed
  5. Mol Microbiol. 2007 Mar;63(5):1399-413 - PubMed
  6. Lancet Infect Dis. 2002 Feb;2(2):73-85 - PubMed
  7. Antimicrob Agents Chemother. 2002 Sep;46(9):3001-12 - PubMed
  8. J Clin Microbiol. 2008 Jan;46(1):150-6 - PubMed
  9. Lancet. 2003 Oct 4;362(9390):1142-51 - PubMed
  10. Science. 1996 Apr 12;272(5259):279-81 - PubMed
  11. Antimicrob Agents Chemother. 2009 Sep;53(9):3690-9 - PubMed
  12. Antimicrob Agents Chemother. 2009 Jan;53(1):112-22 - PubMed
  13. Antimicrob Agents Chemother. 2006 Aug;50(8):2829-32 - PubMed
  14. Antimicrob Agents Chemother. 2009 Mar;53(3):1185-93 - PubMed
  15. Mol Microbiol. 2008 May;68(3):624-41 - PubMed
  16. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9284-9 - PubMed
  17. Antimicrob Agents Chemother. 2007 Jun;51(6):2253-6 - PubMed
  18. Science. 2006 Jul 21;313(5785):367-70 - PubMed
  19. Antimicrob Agents Chemother. 2010 Jun;54(6):2655-9 - PubMed
  20. Eukaryot Cell. 2003 Dec;2(6):1200-10 - PubMed
  21. Antimicrob Agents Chemother. 2010 May;54(5):2225-7 - PubMed
  22. Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12907-11 - PubMed
  23. PLoS Pathog. 2008 Apr 04;4(4):e1000040 - PubMed
  24. Antimicrob Agents Chemother. 2005 Aug;49(8):3264-73 - PubMed
  25. Fungal Genet Biol. 2010 Feb;47(2):117-26 - PubMed
  26. Antimicrob Agents Chemother. 1997 Nov;41(11):2471-9 - PubMed
  27. Genetics. 2003 Apr;163(4):1287-98 - PubMed
  28. J Clin Microbiol. 2010 Jul;48(7):2373-80 - PubMed
  29. Antimicrob Agents Chemother. 2009 Feb;53(2):476-82 - PubMed

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