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Reddy SG, Reddy RR, Bronkhorst EM, et al. Incidence of cleft Lip and palate in the state of Andhra Pradesh, South India. Indian J Plast Surg. 2010;43(2):184-9doi: 10.4103/0970-0358.73443.
Reddy, S. G., Reddy, R. R., Bronkhorst, E. M., Prasad, R., Ettema, A. M., Sailer, H. F., & Bergé, S. J. (2010). Incidence of cleft Lip and palate in the state of Andhra Pradesh, South India. Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India, 43(2), 184-9. https://doi.org/10.4103/0970-0358.73443
Reddy, Srinivas Gosla, et al. "Incidence of cleft Lip and palate in the state of Andhra Pradesh, South India." Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India vol. 43,2 (2010): 184-9. doi: https://doi.org/10.4103/0970-0358.73443
Reddy SG, Reddy RR, Bronkhorst EM, Prasad R, Ettema AM, Sailer HF, Bergé SJ. Incidence of cleft Lip and palate in the state of Andhra Pradesh, South India. Indian J Plast Surg. 2010 Jul;43(2):184-9. doi: 10.4103/0970-0358.73443. PMID: 21217978; PMCID: PMC3010780.
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Indian J Plast Surg. 2010 Jul;43(2):184-9. doi: 10.4103/0970-0358.73443.

Incidence of cleft Lip and palate in the state of Andhra Pradesh, South India.

Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India

Srinivas Gosla Reddy, Rajgopal R Reddy, Ewald M Bronkhorst, Rajendra Prasad, Anke M Ettema, Hermann F Sailer, Stefaan J Bergé

Affiliations

  1. GSR Institute of Craniofacial Surgery, Hyderabad, Andhra Pradesh, India.

PMID: 21217978 PMCID: PMC3010780 DOI: 10.4103/0970-0358.73443

Abstract

OBJECTIVE: To assess the incidence of cleft lip and palate defects in the state of Andhra Pradesh, India.

DESIGN SETTING: The study was conducted in 2001 in the state of Andhra Pradesh, India. The state has a population of 76 million. Three districts, Cuddapah, Medak and Krishna, were identified for this study owing to their diversity. They were urban, semi-urban and rural, respectively. Literacy rates and consanguinity of the parents was elicited and was compared to national averages to find correlations to cleft births. Type and side of cleft were recorded to compare with other studies around the world and other parts of India.

RESULTS: The birth rate of clefts was found to be 1.09 for every 1000 live births. This study found that 65% of the children born with clefts were males. The distribution of the type of cleft showed 33% had CL, 64% had CLP, 2% had CP and 1% had rare craniofacial clefts. Unilateral cleft lips were found in 79% of the patients. Of the unilateral cleft lips 64% were left sided. There was a significant correlation of children with clefts being born to parents who shared a consanguineous relationship and those who were illiterate with the odds ratio between 5.25 and 7.21 for consanguinity and between 1.55 and 5.85 for illiteracy, respectively.

CONCLUSION: The birth rate of clefts was found to be comparable with other Asian studies, but lower than found in other studies in Caucasian populations and higher than in African populations. The incidence was found to be similar to other studies done in other parts of India. The distribution over the various types of cleft was comparable to that found in other studies.

Keywords: Cleft lip & paplate incidence; cleft lip; cleft palate

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