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Pradhan P, Damania D, Joshi HM, et al. Quantification of nanoscale density fluctuations using electron microscopy: Light-localization properties of biological cells. Appl Phys Lett. 2010;97(24):243704doi: 10.1063/1.3524523.
Pradhan, P., Damania, D., Joshi, H. M., Turzhitsky, V., Subramanian, H., Roy, H. K., Taflove, A., Dravid, V. P., & Backman, V. (2010). Quantification of nanoscale density fluctuations using electron microscopy: Light-localization properties of biological cells. Applied physics letters, 97(24), 243704. https://doi.org/10.1063/1.3524523
Pradhan, Prabhakar, et al. "Quantification of nanoscale density fluctuations using electron microscopy: Light-localization properties of biological cells." Applied physics letters vol. 97,24 (2010): 243704. doi: https://doi.org/10.1063/1.3524523
Pradhan P, Damania D, Joshi HM, Turzhitsky V, Subramanian H, Roy HK, Taflove A, Dravid VP, Backman V. Quantification of nanoscale density fluctuations using electron microscopy: Light-localization properties of biological cells. Appl Phys Lett. 2010 Dec 13;97(24):243704. doi: 10.1063/1.3524523. Epub 2010 Dec 17. PMID: 21221251; PMCID: PMC3017571.
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Appl Phys Lett. 2010 Dec 13;97(24):243704. doi: 10.1063/1.3524523. Epub 2010 Dec 17.

Quantification of nanoscale density fluctuations using electron microscopy: Light-localization properties of biological cells.

Applied physics letters

Prabhakar Pradhan, Dhwanil Damania, Hrushikesh M Joshi, Vladimir Turzhitsky, Hariharan Subramanian, Hemant K Roy, Allen Taflove, Vinayak P Dravid, Vadim Backman

PMID: 21221251 PMCID: PMC3017571 DOI: 10.1063/1.3524523

Abstract

We report a study of the nanoscale mass-density fluctuations of heterogeneous optical dielectric media, including nanomaterials and biological cells, by quantifying their nanoscale light-localization properties. Transmission electron microscope images of the media are used to construct corresponding effective disordered optical lattices. Light-localization properties are studied by the statistical analysis of the inverse participation ratio (IPR) of the localized eigenfunctions of these optical lattices at the nanoscale. We validated IPR analysis using nanomaterials as models of disordered systems fabricated from dielectric nanoparticles. As an example, we then applied such analysis to distinguish between cells with different degrees of aggressive malignancy.

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