World J Cardiol. 2010 Mar 26;2(3):50-2. doi: 10.4330/wjc.v2.i3.50.

Need for new materials, biofunctionalization and non-surgical heart valve technology.

World journal of cardiology

Jan Sochman

PMID: 21160755 PMCID: PMC2999027 DOI: 10.4330/wjc.v2.i3.50

Abstract

Transition from non-surgical heart valve defects repair from bench to bedside is a reality. Some biological material-based designs for transcatheter aortic valve implantation are ready for use. Their drawback, however is their unknown functional as well as structural durability. Moreover, research on new non-biological materials is essential to replace classical animal-derived sources of human heart valve prostheses.

Keywords: Aortic valve; Biomaterials; Heart valve prosthesis; Non-biological materials

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