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Fishman GI. Connexins and the heart. Trends Cardiovasc Med. 1992;2(2):50-5doi: 10.1016/1050-1738(92)90004-C.
Fishman, G. I. (1992). Connexins and the heart. Trends in cardiovascular medicine, 2(2), 50-5. https://doi.org/10.1016/1050-1738(92)90004-C
Fishman, G I. "Connexins and the heart." Trends in cardiovascular medicine vol. 2,2 (1992): 50-5. doi: https://doi.org/10.1016/1050-1738(92)90004-C
Fishman GI. Connexins and the heart. Trends Cardiovasc Med. 1992 Mar-Apr;2(2):50-5. doi: 10.1016/1050-1738(92)90004-C. PMID: 21239274.
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Trends Cardiovasc Med. 1992 Mar-Apr;2(2):50-5. doi: 10.1016/1050-1738(92)90004-C.

Connexins and the heart.

Trends in cardiovascular medicine

G I Fishman

Affiliations

  1. Department of Medicine, Cardiology Division, and the Department of Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

PMID: 21239274 DOI: 10.1016/1050-1738(92)90004-C

Abstract

Gap junctions are specialized regions of adjoining cell membranes composed of numerous intercellular low-resistance channels. In the heart, these channels electrotonically couple adjacent myocytes and synchronize the cardiac action potential. Signaling through gap junction channels may also influence embryogenesis and development. Recent studies have identified the connexin gene family whose protein products assemble to form gap junction channels. Studies of connexin gene expression and function are providing new insights into the behavior of gap junction channels in the heart.

Copyright © 1992. Published by Elsevier Inc.

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