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Onakpoya I, Hung SK, Perry R, et al. The Use of Garcinia Extract (Hydroxycitric Acid) as a Weight loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials. J Obes. 2010;2011:509038doi: 10.1155/2011/509038.
Onakpoya, I., Hung, S. K., Perry, R., Wider, B., & Ernst, E. (2011). The Use of Garcinia Extract (Hydroxycitric Acid) as a Weight loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials. Journal of obesity, 2011509038. https://doi.org/10.1155/2011/509038
Onakpoya, Igho, et al. "The Use of Garcinia Extract (Hydroxycitric Acid) as a Weight loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials." Journal of obesity vol. 2011 (2011): 509038. doi: https://doi.org/10.1155/2011/509038
Onakpoya I, Hung SK, Perry R, Wider B, Ernst E. The Use of Garcinia Extract (Hydroxycitric Acid) as a Weight loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials. J Obes. 2011;2011:509038. doi: 10.1155/2011/509038. Epub 2010 Dec 14. PMID: 21197150; PMCID: PMC3010674.
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J Obes. 2011;2011:509038. doi: 10.1155/2011/509038. Epub 2010 Dec 14.

The Use of Garcinia Extract (Hydroxycitric Acid) as a Weight loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials.

Journal of obesity

Igho Onakpoya, Shao Kang Hung, Rachel Perry, Barbara Wider, Edzard Ernst

Affiliations

  1. Peninsula Medical School, University of Exeter, Devon EX2 4NT, UK.

PMID: 21197150 PMCID: PMC3010674 DOI: 10.1155/2011/509038

Abstract

The aim of this systematic review is to examine the efficacy of Garcinia extract, hydroxycitric acid (HCA) as a weight reduction agent, using data from randomised clinical trials (RCTs). Electronic and nonelectronic searches were conducted to identify relevant articles, with no restrictions in language or time. Two independent reviewers extracted the data and assessed the methodological quality of included studies. Twenty-three eligible trials were identified and twelve were included. Nine trials provided data suitable for statistical pooling. The meta-analysis revealed a small, statistically significant difference in weight loss favouring HCA over placebo (MD: -0.88 kg; 95% CI: -1.75, -0.00). Gastrointestinal adverse events were twice as common in the HCA group compared with placebo in one included study. It is concluded that the RCTs suggest that Garcinia extracts/HCA can cause short-term weight loss. The magnitude of the effect is small, and the clinical relevance is uncertain. Future trials should be more rigorous and better reported.

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