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Ron Y, Sperber AD, Levine A, et al. Early satiety is the only patient-reported symptom associated with delayed gastric emptying, as assessed by breath-test. J Neurogastroenterol Motil. 2011;17(1):61-6doi: 10.5056/jnm.2011.17.1.61.
Ron, Y., Sperber, A. D., Levine, A., Shevah, O., Dickman, R., Avni, Y., & Shirin, H. (2011). Early satiety is the only patient-reported symptom associated with delayed gastric emptying, as assessed by breath-test. Journal of neurogastroenterology and motility, 17(1), 61-6. https://doi.org/10.5056/jnm.2011.17.1.61
Ron, Yishai, et al. "Early satiety is the only patient-reported symptom associated with delayed gastric emptying, as assessed by breath-test." Journal of neurogastroenterology and motility vol. 17,1 (2011): 61-6. doi: https://doi.org/10.5056/jnm.2011.17.1.61
Ron Y, Sperber AD, Levine A, Shevah O, Dickman R, Avni Y, Shirin H. Early satiety is the only patient-reported symptom associated with delayed gastric emptying, as assessed by breath-test. J Neurogastroenterol Motil. 2011 Jan;17(1):61-6. doi: 10.5056/jnm.2011.17.1.61. Epub 2011 Jan 26. PMID: 21369493; PMCID: PMC3042221.
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J Neurogastroenterol Motil. 2011 Jan;17(1):61-6. doi: 10.5056/jnm.2011.17.1.61. Epub 2011 Jan 26.

Early satiety is the only patient-reported symptom associated with delayed gastric emptying, as assessed by breath-test.

Journal of neurogastroenterology and motility

Yishai Ron, Ami D Sperber, Arie Levine, Orit Shevah, Ram Dickman, Yona Avni, Haim Shirin

Affiliations

  1. Department of Gastroenterology and Hepatology, Sourasky Medical Center, Tel-Aviv, Israel.

PMID: 21369493 PMCID: PMC3042221 DOI: 10.5056/jnm.2011.17.1.61

Abstract

BACKGROUND/AIMS: To evaluate associations between delayed gastric emptying (GE) assessed by the octanoic acid breath test and upper gastrointestinal (GI) symptoms.

METHODS: A historical, prospective study included 111 consecutive symptomatic adults referred for a GE breath test because of upper abdominal symptoms suggestive of delayed GE. Exclusion criteria included underlying organic disease associated with delayed GE. Patients completed a symptom questionnaire and underwent a GE octanoic breath test. Patients with delayed GE were compared with those with normal results, for upper GI symptoms.

RESULTS: Early satiety was the only symptom significantly associated with delayed GE. It was observed in 52% of subjects with delayed GE compared to 33% patients with no evidence of delayed GE (P = 0.005). This association was seen for all degrees of severity of delayed GE. Patients with early satiety had a t(1/2) of 153.9 ± 84.6 minutes compared to 110.9 ± 47.6 minutes in subjects without it (P = 0.002). In a logistic regression model, early satiety was significantly associated with delayed GE (OR, 2.29; 95% CI, 1.01-5.18; P = 0.048).

CONCLUSIONS: Early satiety is the only patient-reported GI symptom associated with delayed GE. The utility of GE tests as a clinical diagnostic tool in the work-up of dyspeptic symptoms may be overrated.

Keywords: Breath tests; Dyspepsia; Gastric emptying

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