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Blood. 2011 Mar 03;117(9):2564-5. doi: 10.1182/blood-2011-01-327296.

Breakup feared after filamin leaves GPIb.

Blood

Michelle A Berny-Lang, Owen J T McCarty

Affiliations

  1. Oregon Health & Science University, USA.

PMID: 21372161 DOI: 10.1182/blood-2011-01-327296

Abstract

In this issue of Blood, Cranmer and colleagues demonstrate that the linkage between the cytoskeletal protein filamin A and the platelet receptor glycoprotein (GP) Ibα provides structural integrity to the plasma membrane during platelet adhesion to von Willebrand factor (VWF) under high shear.

© 2011 by The American Society of Hematology

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