Display options
Cite
Kuhls AT, Patel V, Ionita C, et al. New microangiography system development providing improved small vessel imaging, increased contrast to noise ratios, and multi-view 3D reconstructions. Proc SPIE Int Soc Opt Eng. 2006;6142doi: 10.1117/12.653654.
Kuhls, A. T., Patel, V., Ionita, C., Noël, P. B., Walczak, A. M., Rangwala, H. S., Hoffmann, K. R., & Rudin, S. (2006). New microangiography system development providing improved small vessel imaging, increased contrast to noise ratios, and multi-view 3D reconstructions. Proceedings of SPIE--the International Society for Optical Engineering, 6142. https://doi.org/10.1117/12.653654
Kuhls, Andrew T, et al. "New microangiography system development providing improved small vessel imaging, increased contrast to noise ratios, and multi-view 3D reconstructions." Proceedings of SPIE--the International Society for Optical Engineering vol. 6142 (2006). doi: https://doi.org/10.1117/12.653654
Kuhls AT, Patel V, Ionita C, Noël PB, Walczak AM, Rangwala HS, Hoffmann KR, Rudin S. New microangiography system development providing improved small vessel imaging, increased contrast to noise ratios, and multi-view 3D reconstructions. Proc SPIE Int Soc Opt Eng. 2006;6142. doi: 10.1117/12.653654. PMID: 21311731; PMCID: PMC3035357.
Copy Download .nbib Format: NLM
Share it on

Proc SPIE Int Soc Opt Eng. 2006;6142. doi: 10.1117/12.653654.

New microangiography system development providing improved small vessel imaging, increased contrast to noise ratios, and multi-view 3D reconstructions.

Proceedings of SPIE--the International Society for Optical Engineering

Andrew T Kuhls, Vikas Patel, Ciprian Ionita, Peter B Noël, Alan M Walczak, Hussain S Rangwala, Kenneth R Hoffmann, Stephen Rudin

Affiliations

  1. University at Buffalo (State University of New York), Toshiba Stroke Research Center, 3435 Main St., Buffalo, NY USA 14214.

PMID: 21311731 PMCID: PMC3035357 DOI: 10.1117/12.653654

Abstract

A new microangiographic system (MA) integrated into a c-arm gantry has been developed allowing precise placement of a MA at the exact same angle as the standard x-ray image intensifier (II) with unchanged source and object position. The MA can also be arbitrarily moved about the object and easily moved into the field of view (FOV) in front of the lower resolution II when higher resolution angiographic sequences are needed. The benefits of this new system are illustrated in a neurovascular study, where a rabbit is injected with contrast media for varying oblique angles. Digital subtraction angiographic (DSA) images were obtained and compared using both the MA and II detectors for the same projection view. Vessels imaged with the MA appear sharper with smaller vessels visualized. Visualization of ~100 μm vessels was possible with the MA whereas not with the II. Further, the MA could better resolve vessel overlap. Contrast to noise ratios (CNR) were calculated for vessels of varying sizes for the MA versus the II and were found to be similar for large vessels, approximately double for medium vessels, and infinitely better for the smallest vessels. In addition, a 3D reconstruction of selected vessel segments was performed, using multiple (three) projections at oblique angles, for each detector. This new MA/II integrated system should lead to improved diagnosis and image guidance of neurovascular interventions by enabling initial guidance with the low resolution large FOV II combined with use of the high resolution MA during critical parts of diagnostic and interventional procedures.

References

  1. Med Phys. 2002 Jul;29(7):1622-33 - PubMed
  2. Proc SPIE Int Soc Opt Eng. 2006;6142: - PubMed
  3. Med Phys. 1987 Jul-Aug;14(4):549-56 - PubMed
  4. Med Phys. 2003 Apr;30(4):681-8 - PubMed
  5. Proc SPIE Int Soc Opt Eng. 2005;5744(1):354-365 - PubMed
  6. Med Phys. 2003 Nov;30(11):3018-28 - PubMed
  7. Med Phys. 2003 Nov;30(11):3029-39 - PubMed
  8. Proc SPIE Int Soc Opt Eng. 2005;5745(1):419-429 - PubMed

Publication Types

Grant support