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Mcgill J Med. 2009 Nov 16;12(2):14.

Disseminated Coccidioidomycosis with Clinically Evident Splenomegaly in an Immunocompetent Host, First Case Reported in the literature.

McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students

Garrett R Bird, Robert D Libke, John F Billelo, Nancy A Parks, John S Pollard

PMID: 21264046 PMCID: PMC2997246

Abstract

Coccidioidomycosis is a dimorphic fungus endemic to the southwestern United States, Central and South America. We report a case of a previously healthy person who presented with respiratory failure and disseminated Coccidioidomycosis who eventually had a fatal outcome. Coccidioidomycosis, or "Valley Fever" has been called the "great imitator" (1) as it can have a wide variety of clinical presentations. This case is unique as it represents the first described case of an immunocompetent host with rapidly progressing, disseminated coccidioidomycosis with clinically apparent splenomegaly and hepatomegaly.

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