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Spanel P, Dryahina K, Smith D. The concentration distributions of some metabolites in the exhaled breath of young adults. J Breath Res. 2007;1(2):026001doi: 10.1088/1752-7155/1/2/026001.
Spanel, P., Dryahina, K., & Smith, D. (2007). The concentration distributions of some metabolites in the exhaled breath of young adults. Journal of breath research, 1(2), 026001. https://doi.org/10.1088/1752-7155/1/2/026001
Spanel, Patrik, et al. "The concentration distributions of some metabolites in the exhaled breath of young adults." Journal of breath research vol. 1,2 (2007): 026001. doi: https://doi.org/10.1088/1752-7155/1/2/026001
Spanel P, Dryahina K, Smith D. The concentration distributions of some metabolites in the exhaled breath of young adults. J Breath Res. 2007 Dec;1(2):026001. doi: 10.1088/1752-7155/1/2/026001. Epub 2007 Oct 16. PMID: 21383435.
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J Breath Res. 2007 Dec;1(2):026001. doi: 10.1088/1752-7155/1/2/026001. Epub 2007 Oct 16.

The concentration distributions of some metabolites in the exhaled breath of young adults.

Journal of breath research

Patrik Spanel, Kseniya Dryahina, David Smith

Affiliations

  1. J Heyrovský Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, Dolejškova 3, 182 23, Prague 8, Czech Republic.

PMID: 21383435 DOI: 10.1088/1752-7155/1/2/026001

Abstract

The concentrations of ammonia, acetone, methanol, ethanol, propanol and hydrogen cyanide have been measured in the exhaled breath of 26 young adults of age 17/18 years, using selected ion flow tube mass spectrometry (SIFT-MS). Thus the concentration distributions have been constructed and are seen to be essentially log normal with median values in parts per billion (ppb), being ammonia, 317; acetone, 363; methanol, 238; ethanol, 104; propanol, 13; hydrogen cyanide (HCN), 8. There is a clear separation in the median breath ethanol levels between those volunteers who had ingested sugary food/drinks (109 ppb) and those who had not (48 ppb). These data are compared with the results of a study of the same breath compounds, excepting HCN, for a similar sized cohort of healthy volunteers within the age range of 20 to 60 years, which shows that the median levels of these compounds are lower in the young adult volunteer cohort. These HCN measurements are the first to be made in the breath of healthy individuals. The potential implications of these combined results for clinical diagnosis are alluded to.

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