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Can J Infect Dis Med Microbiol. 2010;21(1):53-6. doi: 10.1155/2010/679604.

Blastomycosis presenting as multiple splenic abscesses: Case report and review of the literature.

The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

Sami Al-Nassar, Tracy Macnair, Jeremy Lipschitz, Howard Greenberg, Elly Trepman, Sate Hamza, John M Embil

Affiliations

  1. Department of Surgery, King Saud University, Riyadh, Saudi Arabia;

PMID: 21358886 PMCID: PMC2852283 DOI: 10.1155/2010/679604

Abstract

A 31-year-old Canadian Aboriginal man from northwestern Ontario presented with left upper quadrant pain and a tender left upper quadrant mass. Evaluation with a computed tomography scan showed multiple lesions within the spleen, a collection between the splenic tip and splenic flexure of the colon, and several small adrenal lesions. Computed tomographic-guided needle biopsy showed necrotizing granulomatous inflammation and multinucleated giant cells. Gomori's methenamine silver stain showed broad-based budding yeast consistent with Blastomyces dermatitidis. Abdominal symptoms resolved after two months of oral itraconazole. Multiple splenic abscesses are a rare presentation of blastomycosis and should be considered in the differential diagnosis of left upper quadrant abdominal pain in a patient with a history of travel or residence in a region endemic for B dermatitidis.

Keywords: Abdominal pain; Blastomyces dermatitidis; Fungus; Spleen

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