Display options
Cite
Tanaka Y, Matsuo K, Yuzuriha S. Near-Infrared Irradiation Nonthermally Induces Long-lasting Vasodilation by Causing Apoptosis of Vascular Smooth Muscle Cells. Eplasty. 2011;11:e22
Tanaka, Y., Matsuo, K., & Yuzuriha, S. (2011). Near-Infrared Irradiation Nonthermally Induces Long-lasting Vasodilation by Causing Apoptosis of Vascular Smooth Muscle Cells. Eplasty, 11e22.
Tanaka, Yohei, et al. "Near-Infrared Irradiation Nonthermally Induces Long-lasting Vasodilation by Causing Apoptosis of Vascular Smooth Muscle Cells." Eplasty vol. 11 (2011): e22.
Tanaka Y, Matsuo K, Yuzuriha S. Near-Infrared Irradiation Nonthermally Induces Long-lasting Vasodilation by Causing Apoptosis of Vascular Smooth Muscle Cells. Eplasty. 2011 May 02;11:e22. PMID: 21559319; PMCID: PMC3086536.
Copy Download .nbib Format: NLM
Share it on

Eplasty. 2011 May 02;11:e22.

Near-Infrared Irradiation Nonthermally Induces Long-lasting Vasodilation by Causing Apoptosis of Vascular Smooth Muscle Cells.

Eplasty

Yohei Tanaka, Kiyoshi Matsuo, Shunsuke Yuzuriha

Affiliations

  1. Department of Plastic and Reconstructive Surgery Shinshu University School of Medicine, Matsumoto, Japan.

PMID: 21559319 PMCID: PMC3086536

Abstract

BACKGROUND: Moderate sunburn after prolonged sun exposure is thought to cause long-lasting inflammatory vasodilation due to thermal and ultraviolet radiation from the sun. We previously reported that near-infrared irradiation that simulates solar near-infrared can penetrate the skin and nonthermally affect the dermis, superficial muscles, and other tissues. To clarify the possible effect of near-infrared on long-lasting vasodilation, we evaluated how near-infrared affects subcutaneous vascular smooth muscle cells in rats.

METHODS: The central back tissues of rats were irradiated with a near-infrared device that simulates solar radiation, which has specialized contact cooling to avoid thermal effects. The total energy emitted was equivalent to approximately 8.75 hours of sunbathing in North America. Histological evaluation was performed on the subdermal plexus over the panniculus carnosus muscle of the near-infrared-irradiated rats at postirradiation days 7, 30, 60, and 90, and compared with nonirradiated controls. The vascular smooth muscle cells were evaluated by the transferase-mediated dUTP nick-end labeling assay and staining with an anti-smooth muscle actin antibody.

RESULTS: There was no evidence of inflammation by the increased movement of leucocytes around the dilated vessels in irradiated samples. Near-infrared irradiation induced apoptosis of the vascular smooth muscle cells and significantly induced intense, long-lasting vasodilation of the subdermal plexus at postirradiation day 7.

CONCLUSIONS: Near-infrared irradiation nonthermally induces long-lasting vasodilation by causing apoptosis of vascular smooth muscle cells. Since solar near-infrared radiation nonthermally induces damage of the subcutaneous tissues, exposed skin should be protected with sunscreens that block not only ultraviolet but also near-infrared radiation.

References

  1. Clin Cosmet Investig Dermatol. 2010 Nov 25;3:143-9 - PubMed
  2. Lasers Surg Med. 1994;14(4):355-61 - PubMed
  3. Dermatol Surg. 2009 Jul;35(7):1099-104 - PubMed
  4. FEBS Lett. 1984 Sep 17;175(1):95-9 - PubMed
  5. Calcif Tissue Int. 1996 Oct;59(4):297-300 - PubMed
  6. Eplasty. 2011 Mar 09;11:e12 - PubMed
  7. Lasers Surg Med. 1998;22(5):294-301 - PubMed
  8. Science. 1966 Feb 4;151(3710):523-9 - PubMed
  9. Ann Dermatol. 2009 Aug;21(3):243-9 - PubMed
  10. J Clin Laser Med Surg. 1998 Jun;16(3):159-65 - PubMed
  11. Eplasty. 2011 Feb 16;11:e6 - PubMed
  12. Rheumatol Int. 2004 Sep;24(5):260-3 - PubMed
  13. J Drugs Dermatol. 2009 Aug;8(8):708-12 - PubMed
  14. J Clin Periodontol. 1996 May;23(5):492-6 - PubMed
  15. Eplasty. 2010 May 28;10:e40 - PubMed
  16. Cell Mol Biol (Noisy-le-grand). 2001;47 Online Pub:OL131-4 - PubMed
  17. Brain Res. 1989 Jan 9;476(2):205-12 - PubMed
  18. Photodermatol. 1989 Apr;6(2):80-4 - PubMed
  19. Photochem Photobiol. 1997 Dec;66(6):866-71 - PubMed
  20. J Am Acad Dermatol. 1988 May;18(5 Pt 1):1003-19 - PubMed
  21. Cancer Sci. 2010 Jun;101(6):1396-402 - PubMed
  22. Photomed Laser Surg. 2006 Apr;24(2):111-20 - PubMed
  23. J Photochem Photobiol B. 1999 Mar;49(1):1-17 - PubMed

Publication Types